Alcoholic liver disease: pathogenesis and new therapeutic targets

B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …

Recent advances in understanding of pathogenesis of alcohol-associated liver disease

X Wu, X Fan, T Miyata, A Kim… - Annual Review of …, 2023 - annualreviews.org
Alcohol-associated liver disease (ALD) is one of the major diseases arising from chronic
alcohol consumption and is one of the most common causes of liver-related morbidity and …

Advances in alcoholic liver disease

JI Beier, GE Arteel, CJ McClain - Current gastroenterology reports, 2011 - Springer
Alcoholic liver disease (ALD) remains a leading cause of death from liver disease in the
United States. In studies from the Veterans Administration, patients with cirrhosis and …

[HTML][HTML] Alcoholic liver disease: A current molecular and clinical perspective

K Ohashi, M Pimienta, E Seki - Liver research, 2018 - Elsevier
Heavy alcohol use is the cause of alcoholic liver disease (ALD). The ALD spectrum ranges
from alcoholic steatosis to steatohepatitis, fibrosis, and cirrhosis. In Western countries …

Alcoholic liver disease: pathogenesis, management, and novel targets for therapy

ES Orman, G Odena, R Bataller - Journal of gastroenterology …, 2013 - Wiley Online Library
Alcohol use is a leading cause of preventable morbidity and mortality worldwide, with much
of its negative impact as the result of alcoholic liver disease (ALD). ALD is a broad term that …

Mechanisms and cell signaling in alcoholic liver disease

JI Beier, CJ McClain - 2010 - degruyter.com
Alcoholic liver disease (ALD) remains a major cause of morbidity and mortality worldwide.
For example, the Veterans Administration Cooperative Studies reported that patients with …

Alcoholic liver disease: new insights in pathogenesis lead to new treatments

CS Lieber - Journal of hepatology, 2000 - Elsevier
Much progress has been made in the understanding of the pathogenesis of alcoholic liver
disease, resulting in improvement of prevention and therapy, with promising prospects for …

Alcoholic liver disease: pathogenesis and new targets for therapy

J Altamirano, R Bataller - Nature reviews Gastroenterology & …, 2011 - nature.com
Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. The
spectrum of disease ranges from fatty liver to hepatic inflammation, necrosis, progressive …

Pathogenesis of alcohol-associated liver disease

NA Osna, K Rasineni, M Ganesan… - Journal of Clinical and …, 2022 - Elsevier
Excessive alcohol consumption is a global healthcare problem with enormous social,
economic, and clinical consequences. While chronic, heavy alcohol consumption causes …

Alcoholic liver disease: mechanisms of injury and targeted treatment

A Louvet, P Mathurin - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
Alcoholic liver disease (ALD) is a complex process that includes a wide spectrum of hepatic
lesions, from steatosis to cirrhosis. Cell injury, inflammation, oxidative stress, regeneration …