Just at the beginning of the millennium the neologism laminopathies has been introduced in
the scientific vocabulary. An exponential increase of interest on the subject started …

Most inherited diseases are associated with mutations in a specific gene. Sometimes,
mutations in two or more different genes result in diseases with a similar phenotype. Rarely …

A group of human diseases, known as' laminopathies', are associated with defects in
proteins of the nuclear envelope. Most laminopathy mutations have been mapped to the A …

In the past decade, the inner nuclear membrane has become a focus of research on
inherited diseases. A heterogeneous group of genetic disorders known as laminopathies …

Mutations in the lamin A/C gene are involved in multiple human disorders for which the
pathophysiological mechanisms are partially understood. Conflicting results prevail …

Nuclear lamins form a fibrous nucleoskeletal network of intermediate‐sized filaments that
underlies the inner nuclear membrane. It associates with this membrane through …

The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear
pore complexes. In recent years, mutations in nuclear‐envelope proteins have been shown …

Mutations in genes encoding nuclear lamins and associated nuclear envelope proteins
have been linked to a broad range of inherited diseases affecting different tissues and …

Most inherited diseases are associated with mutations in a specific gene. Often, mutations in
two or more different genes result in diseases with a similar phenotype. Rarely do different …

The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear
pore complexes. Laminopathies are diseases caused by mutations in genes encoding …