Atypical hemolytic uremic syndrome: from the rediscovery of complement to targeted therapy
F Fakhouri, V Frémeaux-Bacchi, C Loirat - European Journal of Internal …, 2013 - Elsevier
Atypical hemolytic uremic syndrome (aHUS) is a devastating form of renal thrombotic
microangiopathy. In the last five years, we have finally witnessed a dramatic improvement in …
microangiopathy. In the last five years, we have finally witnessed a dramatic improvement in …
Belgian consensus statement on the diagnosis and management of patients with atypical hemolytic uremic syndrome
KJ Claes, A Massart, L Collard, L Weekers… - Acta Clinica …, 2018 - Taylor & Francis
In the last decade, significant progress has been made in the understanding and the
treatment of patients with atypical Hemolytic Uremic Syndrome (aHUS). aHUS has emerged …
treatment of patients with atypical Hemolytic Uremic Syndrome (aHUS). aHUS has emerged …
Safety and effectiveness of restrictive eculizumab treatment in atypical haemolytic uremic syndrome
KL Wijnsma, C Duineveld, EB Volokhina… - Nephrology Dialysis …, 2018 - academic.oup.com
Background Atypical haemolytic uremic syndrome (aHUS) is a rare but severe form of
thrombotic microangiopathy as a consequence of complement dysregulation. aHUS has a …
thrombotic microangiopathy as a consequence of complement dysregulation. aHUS has a …
A complicated case of atypical hemolytic uremic syndrome with frequent relapses under eculizumab
G Schalk, M Kirschfink, C Wehling, S Gastoldi… - Pediatric …, 2015 - Springer
Background Atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic
microangiopathy characterized by uncontrolled activation of the alternative complement …
microangiopathy characterized by uncontrolled activation of the alternative complement …
[PDF][PDF] Defining treatment duration in atypical hemolytic uremic syndrome in adults: a clinical and pathological approach
J Laurence - Clin Adv Hematol Oncol, 2020 - hematologyandoncology.net
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that is
driven by uncontrolled activation of the alternative complement pathway, classically in the …
driven by uncontrolled activation of the alternative complement pathway, classically in the …
Discontinuation of eculizumab maintenance treatment for atypical hemolytic uremic syndrome: a report of 10 cases
G Ardissino, S Testa, I Possenti, F Tel… - American Journal of …, 2014 - Elsevier
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening thrombotic
microangiopathy, and as many as 70% of patients with aHUS have mutations in the genes …
microangiopathy, and as many as 70% of patients with aHUS have mutations in the genes …
[HTML][HTML] A case of atypical hemolytic uremic syndrome successfully treated with eculizumab
B Thajudeen, A Sussman, E Bracamonte - Case Reports in Nephrology …, 2013 - karger.com
Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy (TMA)
characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal failure …
characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal failure …
Can eculizumab be discontinued in aHUS?: case report and review of the literature
T Sahutoglu, T Basturk, T Sakaci, Y Koc, E Ahbap… - Medicine, 2016 - journals.lww.com
Background: The management of atypical hemolytic uremic syndrome (aHUS) has evolved
into better control of thrombotic microangiopathy (TMA) and recovery of renal functions since …
into better control of thrombotic microangiopathy (TMA) and recovery of renal functions since …
[HTML][HTML] Terminal complement inhibitor eculizumab in adult patients with atypical hemolytic uremic syndrome: a single-arm, open-label trial
F Fakhouri, M Hourmant, JM Campistol… - American journal of …, 2016 - Elsevier
Background Atypical hemolytic uremic syndrome (aHUS) is a rare genetic life-threatening
disease of chronic uncontrolled complement activation leading to thrombotic …
disease of chronic uncontrolled complement activation leading to thrombotic …
[HTML][HTML] Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome
LA Greenbaum, M Fila, G Ardissino, SI Al-Akash… - Kidney international, 2016 - Elsevier
Atypical hemolytic uremic syndrome (aHUS) is caused by alternative complement pathway
dysregulation, leading to systemic thrombotic microangiopathy (TMA) and severe end-organ …
dysregulation, leading to systemic thrombotic microangiopathy (TMA) and severe end-organ …