Hundreds of E3 ligases play a critical role in recognizing specific substrates for modification
by ubiquitin (Ub). Separating genuine targets of E3s from E3-interactors remains a …

Background Cell wall degrading enzymes (CWDEs) induce plant immune responses and E3
ubiquitin ligases are known to play important roles in regulating plant defenses. Expression …

Plant U-box E3 ubiquitin ligases (PUBs) play an important role in growth, development, and
stress responses in many species. However, the characteristics of U-box E3 ubiquitin ligase …

Ubiquitination is an important environmental stress response, and E3 ubiquitin ligases play
a major role in the process. T-DNA insertion mutants of rice, Oscbe1-1, and Oscbe1-2, were …

Since its discovery in the late 1970s, the ubiquitin proteasome pathway appears to be
omnipresent in many research fields. Although originally discovered in animals, the pathway …

Ubiquitination is a post-translational regulatory mechanism that controls a variety of
biological processes in plants. The E3 ligases confer specificity by recognizing target …

Background Ubiquitination is a post-translation modification where ubiquitin is attached to a
substrate. Ubiquitin-conjugating enzymes (E2s) play a major role in the ubiquitin transfer …

Most research in the field of ubiquitination has focused on E3 ubiquitin ligases because they
are the specificity determinants of the ubiquitination process. Nevertheless, E2s are …

The ubiquitin C-terminal hydrolase (UCH) and ubiquitin-specific processing protease (UBP)
protein families both function in protein deubiquitination, playing important roles in a wide …

Attachment of ubiquitin to substrate proteins is catalyzed by the three enzymes E1, E2
(ubiquitin conjugating [UBC]), and E3 (ubiquitin ligase). Forty-one functional proteins with a …