Pathogen evolution in finite populations: slow and steady spreads the best
The theory of life-history evolution provides a powerful framework to understand the
evolutionary dynamics of pathogens. It assumes, however, that host populations are large …
evolutionary dynamics of pathogens. It assumes, however, that host populations are large …
[PDF][PDF] Life-history evolution of class-structured populations in fluctuating environments
What is the influence of periodic environmental fluctuations on life-history evolution? We
present a general theoretical framework to understand and predict the long-term evolution of …
present a general theoretical framework to understand and predict the long-term evolution of …
Antigenic escape selects for the evolution of higher pathogen transmission and virulence
Despite the propensity for complex and non-equilibrium dynamics in nature, eco-
evolutionary analytical theory typically assumes that populations are at equilibria. In …
evolutionary analytical theory typically assumes that populations are at equilibria. In …
Evolution of acute infections and the invasion-persistence trade-off
We seek to understand the conditions favoring the evolution of acute, highly transmissible
infections. Most work on the life-history evolution of pathogens has focused on the …
infections. Most work on the life-history evolution of pathogens has focused on the …
How do fluctuating ecological dynamics impact the evolution of hosts and parasites?
Theoretical models of the evolution of parasites and their hosts have shaped our
understanding of infectious disease dynamics for over 40 years. Many theoretical models …
understanding of infectious disease dynamics for over 40 years. Many theoretical models …
Evolution of class-structured populations in periodic environments
What is the influence of periodic environmental fluctuations on life-history evolution? We
present a general theoretical framework to understand and predict the long-term evolution of …
present a general theoretical framework to understand and predict the long-term evolution of …
Stochasticity generates an evolutionary instability for infectious disease
JM Read, MJ Keeling - Ecology letters, 2007 - Wiley Online Library
Traditional models of disease evolution are based upon the deterministic competition
between strains that confer complete cross‐immunity, and predict the selection of strains …
between strains that confer complete cross‐immunity, and predict the selection of strains …
On the evolutionary dynamics of pathogens with direct and environmental transmission
A number of ecologically and economically important pathogens exhibit a complex
transmission dynamics that involves distinct transmission modes. In this paper, we study the …
transmission dynamics that involves distinct transmission modes. In this paper, we study the …
Evolution of virulence in heterogeneous host communities under multiple trade-offs
Many pathogens and parasites are transmitted through hosts that differ in species, sex,
genotype, or immune status. In addition, virulence (here defined as disease-induced …
genotype, or immune status. In addition, virulence (here defined as disease-induced …
Multiple scales of selection influence the evolutionary emergence of novel pathogens
M Park, C Loverdo, SJ Schreiber… - … Transactions of the …, 2013 - royalsocietypublishing.org
When pathogens encounter a novel environment, such as a new host species or treatment
with an antimicrobial drug, their fitness may be reduced so that adaptation is necessary to …
with an antimicrobial drug, their fitness may be reduced so that adaptation is necessary to …