Pathogen evolution in finite populations: slow and steady spreads the best

TL Parsons, A Lambert, T Day… - Journal of The Royal …, 2018 - royalsocietypublishing.org
The theory of life-history evolution provides a powerful framework to understand the
evolutionary dynamics of pathogens. It assumes, however, that host populations are large …

[PDF][PDF] Life-history evolution of class-structured populations in fluctuating environments

S Lion, S Gandon - bioRxiv, 2021 - academia.edu
What is the influence of periodic environmental fluctuations on life-history evolution? We
present a general theoretical framework to understand and predict the long-term evolution of …

Antigenic escape selects for the evolution of higher pathogen transmission and virulence

A Sasaki, S Lion, M Boots - Nature ecology & evolution, 2022 - nature.com
Despite the propensity for complex and non-equilibrium dynamics in nature, eco-
evolutionary analytical theory typically assumes that populations are at equilibria. In …

Evolution of acute infections and the invasion-persistence trade-off

AA King, S Shrestha, ET Harvill… - The American …, 2009 - journals.uchicago.edu
We seek to understand the conditions favoring the evolution of acute, highly transmissible
infections. Most work on the life-history evolution of pathogens has focused on the …

How do fluctuating ecological dynamics impact the evolution of hosts and parasites?

A Best, B Ashby - … Transactions of the Royal Society B, 2023 - royalsocietypublishing.org
Theoretical models of the evolution of parasites and their hosts have shaped our
understanding of infectious disease dynamics for over 40 years. Many theoretical models …

Evolution of class-structured populations in periodic environments

S Lion, S Gandon - Evolution, 2022 - academic.oup.com
What is the influence of periodic environmental fluctuations on life-history evolution? We
present a general theoretical framework to understand and predict the long-term evolution of …

Stochasticity generates an evolutionary instability for infectious disease

JM Read, MJ Keeling - Ecology letters, 2007 - Wiley Online Library
Traditional models of disease evolution are based upon the deterministic competition
between strains that confer complete cross‐immunity, and predict the selection of strains …

On the evolutionary dynamics of pathogens with direct and environmental transmission

B Boldin, E Kisdi - Evolution, 2012 - academic.oup.com
A number of ecologically and economically important pathogens exhibit a complex
transmission dynamics that involves distinct transmission modes. In this paper, we study the …

Evolution of virulence in heterogeneous host communities under multiple trade-offs

EE Osnas, AP Dobson - Evolution, 2012 - academic.oup.com
Many pathogens and parasites are transmitted through hosts that differ in species, sex,
genotype, or immune status. In addition, virulence (here defined as disease-induced …

Multiple scales of selection influence the evolutionary emergence of novel pathogens

M Park, C Loverdo, SJ Schreiber… - … Transactions of the …, 2013 - royalsocietypublishing.org
When pathogens encounter a novel environment, such as a new host species or treatment
with an antimicrobial drug, their fitness may be reduced so that adaptation is necessary to …