HLA repertoire of 115 UAE nationals infected with SARS-CoV-2

H Alnaqbi, GK Tay, HF Jelinek, A Francis, E Alefishat… - Human Immunology, 2022 - Elsevier
The class I and class II Human Leucocyte Antigens (HLA) are an integral part of the host
adaptive immune system against viral infections. The characterization of HLA allele …

HLA-DRB1* 04 may predict the severity of disease in a group of Iranian COVID-19 patients

S Ebrahimi, HR Ghasemi-Basir, MM Majzoobi… - Human Immunology, 2021 - Elsevier
Human leukocyte antigen (HLA) genes with extreme diversity can make a contribution for
individual variations to the immune response against SARS-COV-2 infection. This study …

Association of HLA gene polymorphism with susceptibility, severity, and mortality of COVID‐19: a systematic review

P Deb, K Zannat, S Talukder, AH Bhuiyan, MSA Jilani… - Hla, 2022 - Wiley Online Library
HLA is crucial for appropriate immune responses in several viral infections, as well as in
severe acute respiratory syndrome coronavirus‐2 (SARS CoV‐2). The unpredictable nature …

[HTML][HTML] Study of HLA-A,-B,-C,-DRB1 and-DQB1 polymorphisms in COVID-19 patients

JF Gutiérrez-Bautista, A Rodriguez-Nicolas… - Journal of Microbiology …, 2022 - Elsevier
Background Human leukocyte antigen (HLA) plays an important role in immune responses
to infections, especially in the development of acquired immunity. Given the high degree of …

Association of HLA class I genotypes with severity of coronavirus disease-19

M Shkurnikov, S Nersisyan, T Jankevic… - Frontiers in …, 2021 - frontiersin.org
Human leukocyte antigen (HLA) class I molecules play a crucial role in the development of a
specific immune response to viral infections by presenting viral peptides at the cell surface …

Association between HLA-C alleles and COVID-19 severity in a pilot study with a Spanish Mediterranean Caucasian cohort

L Vigón, M Galán, M Torres, AJ Martín-Galiano… - PloS One, 2022 - journals.plos.org
The clinical presentations of COVID-19 may range from an asymptomatic or mild infection to
a critical or fatal disease. Several host factors such as elderly age, male gender, and …

HLA alleles associated with COVID-19 susceptibility and severity in different populations: a systematic review

M Fakhkhari, H Caidi, K Sadki - Egyptian Journal of Medical Human …, 2023 - Springer
Background COVID-19 is a respiratory disease caused by a novel coronavirus called as
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Detected for the first …

The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review

T Hoseinnezhad, N Soltani, S Ziarati… - Journal of Clinical …, 2024 - Wiley Online Library
Background The COVID‐19 pandemic has had a profound global impact, with variations in
susceptibility, severity, and mortality rates across different regions. While many factors can …

Protective HLA alleles against severe COVID-19: HLA-A* 68 as an ancestral protection allele in Tapachula-Chiapas, Mexico

S Hernández-Doño, RA Sánchez-González… - Clinical …, 2022 - Elsevier
HLA is a polymorphic antigen presenter which has provided valuable information on the
susceptibility of populations to viruses. Therefore, the study of HLA can reveal specific …

HLA‐A*11:01 and HLA‐C*04:01 are associated with severe COVID‐19

P Castro‐Santos, A Rojas‐Martinez, JA Riancho… - Hla, 2023 - Wiley Online Library
We analyzed the association between HLA polymorphisms and susceptibility to SARS‐CoV‐
2 infection and disease severity. Genotyping data from a total of 9373 COVID‐19‐positive …