The renin–angiotensin system (RAS), in particular angiotensin II, plays an important role in
cardiac remodelling. Angiotensin‐converting enzyme (ACE) and angiotensin‐converting …

Angiotensin-converting enzyme (ACE) 2 is a recently identified homologue of ACE. There is
great interest in the therapeutic benefit for ACE2 overexpression in the heart. However, the …

Angiotensin-converting enzyme 2 (ACE2) preferentially forms angiotensin-(1-7)[ANG-(1-7)]
from ANG II. We showed that cardiac ACE2 is elevated following treatment of coronary artery …

Background Angiotensin‐converting enzyme 3 (ACE 3) is a recently defined homolog of
ACE. However, the pathophysiological function of ACE 3 is largely unknown. Here, we aim …

Angiotensin-converting enzyme 2 (ACE2) has been proposed as a potential target for
cardioprotection in regulating cardiovascular functions, owing to its key role in the formation …

The cardiac renin–angiotensin–aldosterone system (RAAS) is an endocrine cascade, which
results in the conversion of the inactive pro-hormone angiotensin I (Ang I) to the active …

The renin-angiotensin system (RAS) has been recognized for many years as critical
pathway for blood pressure control and kidney functions. Although most of the well-known …

The renin–angiotensin system (RAS) is critically involved in cardiovascular and renal
function and in disease conditions, and has been shown to be a far more complex system …

Aims Angiotensin converting enzyme (ACE) 2 catalyses the cleavage of angiotensin (Ang) I
to Ang 1‐9 and of Ang II to Ang 1‐7. ACE2 deficiency impairs cardiac contractility and …

Angiotensin-converting enzyme (ACE) 2 is a key negative regulator of the renin–angiotensin
system and metabolizes angiotensin II (Ang II) into Ang 1 to 7. Ang II is a vasoactive peptide …