The troubled story of tachykinins and neurokinins

CA Maggi - Trends in Pharmacological Sciences, 2000 - cell.com
A family of peptides that shares a common C-terminal sequence (Phe-X-Gly-Leu-MetNH 2)
exists in mammalian and non-mammalian species. In mammals, three of these peptides …

[引用][C] Nonpeptide antagonists herald new era in tachykinin research

KJ Watling - Trends in pharmacological sciences, 1992 - Elsevier
Throughout the past decade, major advances have been made in our understanding of the
biology of the mammalian tachykinin neuropeptides. It is now well established that …

[引用][C] NK‐2 receptor agonists and antagonists

CA Maggi, R Patacchini, M Astolfi… - Annals of the New …, 1991 - Wiley Online Library
Tachykinins are a family of peptides that share the common C-terminal sequence, Phe-X-Gly-
Leu-Met-NH,. In mammals, at least three different tachykinins, namely, substance P (SP) …

The tachykinin NK1 receptor in the brain: pharmacology and putative functions

A Saria - European journal of pharmacology, 1999 - Elsevier
After its discovery in 1931, substance P (SP) remained the only mammalian member of the
family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing …

Tachykinins and tachykinin receptors: a growing family

JN Pennefather, A Lecci, ML Candenas, E Patak… - Life sciences, 2004 - Elsevier
The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

Tachykinins: receptor to effector

AM Khawaja, DF Rogers - The international journal of biochemistry & cell …, 1996 - Elsevier
Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

[引用][C] Peptide‐based tachykinin NK2 receptor antagonists

L Quartara, P Rovero, CA Maggi - Medicinal research reviews, 1995 - Wiley Online Library
Three members of the tachykinin peptide family have an established role as
neurotransmitters in mammals: substance P (SP), neurokinin A (NKA), and neurokinin B …

Neurokinin-receptor antagonists: pharmacological tools and therapeutic drugs

J Longmore, RG Hill… - Canadian journal of …, 1997 - cdnsciencepub.com
The mammalian tachykinins (substance P, neurokinin A, and neurokinin B) are widely
distributed throughout the central and peripheral nervous systems, where they act as …

Neurokinin receptors in the CNS

A Ribeiro-da-Silva, AL McLeod… - Handbook of chemical …, 2000 - books.google.com
The undecapeptide substance P (SP) and other tachykinins such as neurokinin A
(substance K) and neurokinin B (NKB) represent a family of peptide neurotransmitters and/or …

Tachykinin receptors and receptor subtypes.

R Patacchini, CA Maggi - Archives internationales de …, 1995 - europepmc.org
The tachykinins, substance P, neurokinin A and neurokinin B, are a family of neuropeptides
widely distributed in the mammalian central and peripheral nervous system. In the …