The flavanol (-)-epicatechin and its metabolites protect against oxidative stress in primary endothelial cells via a direct antioxidant effect

EJB Ruijters, AR Weseler, C Kicken… - European Journal of …, 2013 - Elsevier
Accumulating evidence suggests that foods rich in flavanols decrease the risk of developing
cardiovascular diseases. Attenuation of oxidative stress was suggested to contribute to the …

Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase

R Jiménez, R López-Sepúlveda, M Kadmiri… - Free Radical Biology …, 2007 - Elsevier
Red wine polyphenols (RWPs) have been reported to exert beneficial effects in preventing
cardiovascular diseases, such as hypertension. We studied the effects of chronic treatment …

The effects of quercetin supplementation on blood pressure–meta-analysis

J Popiolek-Kalisz, E Fornal - Current Problems in Cardiology, 2022 - Elsevier
The effects of quercetin supplementation on blood pressure (BP) remain unclear. The aim of
this meta-analysis is to summarize data focused on quercetin impact on systolic BP (SBP) …

Vasoprotective endothelial effects of a standardized grape product in humans

AA Chaves, MS Joshi, CM Coyle, JE Brady… - Vascular …, 2009 - Elsevier
The pathogenesis of coronary lesion development is a multi-factorial process involving a
number of different cell types and covariates, and injury and dysfunction of the vascular …

Natural phenolic compounds as cardiovascular therapeutics: potential role of their antiinflammatory effects

F Jiang, GJ Dusting - Current vascular pharmacology, 2003 - ingentaconnect.com
A number of epidemiological studies have shown that diets rich in plant-derived phenolic
compounds reduce the risk of coronary heart disease. The chronic antioxidant and …

Tea flavonoids and cardiovascular diseases: a review

LBM Tijburg, T Mattern, JD Folts… - Critical Reviews in …, 1997 - Taylor & Francis
Cardiovascular diseases (CVD) are diseases of the heart and the blood vessels. In this
article we limit the discussion to those cardiovascular diseases that are major causes of …

Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E–knockout mice by alleviating inflammation and endothelial dysfunction

WM Loke, JM Proudfoot, JM Hodgson… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—Animal and clinical studies have suggested that polyphenols in fruits, red wine,
and tea may delay the development of atherosclerosis through their antioxidant and anti …

Polyphenols and atherosclerosis: A critical review of clinical effects on LDL oxidation

A Ahmadi, T Jamialahmadi, A Sahebkar - Pharmacological Research, 2022 - Elsevier
Atherosclerosis is a major etiology of cardiovascular disease that causes considerable
mortality. Oxidized low-density lipoprotein (oxLDL) is a fundamental attributor to …

Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease

JH Stein, JG Keevil, DA Wiebe, S Aeschlimann… - Circulation, 1999 - Am Heart Assoc
Background—In vitro, the flavonoid components of red wine and purple grape juice are
powerful antioxidants that induce endothelium-dependent vasodilation of vascular rings …

Effects of tea and tea flavonoids on endothelial function and blood pressure: a brief review

JM Hodgson - Clinical and experimental pharmacology and …, 2006 - Wiley Online Library
SUMMARY 1 The consumption of tea worldwide is second only to water. Thus, any
physiological effects of tea could have a significant impact on population health. 2 Tea is the …