[图书][B] Taste-masked and Controlled-release Formulations of Chloroquine

A Ng - 1992 - search.proquest.com
Chloroquine remains the treatment of choice for malaria in many countries despite the
appearance of drug resistance. Even with children, chloroquine is normally administered …

Microencapsulation of chloroquine diphosphate by Eudragit RS100

VMK Ndesendo, W Meixner, W Korsatko… - Journal of …, 1996 - Taylor & Francis
Chloroquine diphosphate, a highly water-soluble drug, was encapsulated by using a non-
solvent addition coarcevation method. The coating material employed was Eudragit RS100 …

Slow release of chloroquine phosphate from multiple taste-masked W/O/W multiple emulsions

A Vaziri, B Warburton - Journal of microencapsulation, 1994 - Taylor & Francis
The efficacy and safety of chloroquine as an antimalarial has contributed to the survival of
millions in the past 50 years. Chloroquine is widely available, cheap, well tolerated and …

The effect of acacia, gelatin and polyvinylpyrrolidone on chloroquine transport from multiple w/o/w emulsions

JA Omotosho - International journal of pharmaceutics, 1990 - Elsevier
The formation of multiple w/o/w emulsions with improved stability due to the formation of
interfacial complex films between acacia, gelatin, polyvinylpyrrolidone and sorbitan …

Hot melt coating technology: influence of Compritol 888 Ato and granule size on chloroquine release.

A Faham, P Prinderre, P Piccerelle, N Farah… - Die …, 2000 - europepmc.org
The tangential spray technique was used to coat chloroquine granules with Compritol 888
Ato in a fluidized bed (Glatt GPCG-1, 1). After validation of the assay method for chloroquine …

Effects of absorption enhancers in chloroquine suppository formulations: I: In vitro release characteristics

CO Onyeji, AS Adebayo, CP Babalola - European journal of pharmaceutical …, 1999 - Elsevier
The need to develop chloroquine suppository formulations that yield optimal bioavailability
of the drug has been emphasized. This study demonstrates the effects of incorporation of …

Preparation and characterization of chloroquine loaded microspheres for prophylactic use

SK Sahu, A Ram - Current Drug Delivery, 2013 - ingentaconnect.com
Malaria is one of the major public health problems in the developing countries. Numbers of
drugs are available for the treatment of malaria but chloroquine diphosphate still remains a …

Studies on the development of taste-masked suspension of chloroquine.

V Chandibhamar, MR Yadav… - Bollettino Chimico …, 2004 - europepmc.org
A non-bitter chloroquine suspension formulation for pediatric use was prepared in the form
of an ion-pair of chloroquine with pamoic acid. Various parameters involved in the …

Comparative in vitro and in vivo study of a sugar‐coated chloroquine preparation marketed in Tanzania versus an ordinary brand

SED Nsimba, Y Aden‐Abdi, G Rimoy… - Journal of clinical …, 2001 - Wiley Online Library
Objective: To investigate the absorption and the quality of a sugar‐coated chloroquine (CQ)
marketed in Tanzania. Method: Twenty healthy volunteers were randomised to take either …

An investigation into the suitability of amidated pectin hydrogel beads as a delivery matrix for chloroquine

O Munjeri, P Hodza, EE Osim… - Journal of pharmaceutical …, 1998 - Elsevier
The aim of the present study was to delay the release of chloroquine to distal parts of the
gastrointestinal tract by using a multiparticulate hydrogel formulation. Amidated pectin …