Inflammatory changes are observed in affected joints of osteoarthritis (OA) patients and are
thought to be involved in the pathology that develops along OA progression. This narrative …

Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

Osteoarthritis (OA) is the most common joint disease that strongly reduces the quality of life
in patients; However, no disease-modifying therapy is available. For a long time, OA was …

Understanding the molecular drivers and feedback loops of osteoarthritis (OA) may provide
future therapeutic strategies to modulate the disease progression. The current paradigm of …

A sharp rise in osteoarthritis (OA) incidence is expected as over 25% of world population
ages in the coming decade. Although OA is considered a degenerative disease, mounting …

Osteoarthritis (OA) is the most common age-related chronic and disabling joint disease.
Long considered to be a “wear and tear” disease, OA is now seen as a low-grade …

Although osteoarthritis (OA) has existed since the dawn of humanity, its pathogenesis
remains poorly understood. OA is no longer considered a “wear and tear” condition but …

Objectives As more has become known of the pathophysiology of osteoarthritis (OA),
evidence that inflammation plays a critical role in its development and progression has …

Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …

The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and
unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly …