[HTML][HTML] Identification of blood-derived candidate gene markers and a new 7-gene diagnostic model for multiple sclerosis

X Chen, H Hou, H Qiao, H Fan, T Zhao, M Dong - Biological Research, 2021 - Springer
Background Multiple sclerosis (MS) is a central nervous system disease with a high
disability rate. Modern molecular biology techniques have identified a number of key genes …

[HTML][HTML] Identification of key genes associated with multiple sclerosis based on gene expression data from peripheral blood mononuclear cells

Z Shang, W Sun, M Zhang, L Xu, X Jia, R Zhang, S Fu - PeerJ, 2020 - peerj.com
The aim of this study was to identify the potential key candidate genes of multiple sclerosis
(MS) and uncover mechanisms in MS. We combined data from the microarray expression …

Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis

SU Kumar, A Datta, R Gnanasambandan… - Advances in protein …, 2022 - Elsevier
Multiple Sclerosis (MS) is a neurodegenerative autoimmune and organ-specific
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …

Microarray gene expression profiling analysis combined with bioinformatics in multiple sclerosis

M Liu, X Hou, P Zhang, Y Hao, Y Yang, X Wu… - Molecular biology …, 2013 - Springer
Multiple sclerosis (MS) is the most prevalent demyelinating disease and the principal cause
of neurological disability in young adults. Recent microarray gene expression profiling …

[HTML][HTML] Transcriptomic analysis of multiple sclerosis patient-derived monocytes by RNA-sequencing for candidate gene discovery

F Almsned, RH Lipsky, MS Jafri - Informatics in Medicine Unlocked, 2021 - Elsevier
Multiple Sclerosis (MS) is an inflammatory disorder associated with immune abnormalities in
the Central Nervous System (CNS), including an abundance of monocytes in MS lesions …

[HTML][HTML] Identification of key genes and microRNAs for multiple sclerosis using bioinformatics analysis

Z Xu, X Feng, W Zhu, M Qiu - Medicine, 2021 - journals.lww.com
To better understand the molecular mechanism underlying the pathogenesis of multiple
sclerosis (MS), we aimed to identify the key genes and microRNAs (miRNA) associated with …

[HTML][HTML] Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis

N Safari-Alighiarloo, M Rezaei-Tavirani, M Taghizadeh… - PeerJ, 2016 - peerj.com
Background The involvement of multiple genes and missing heritability, which are dominant
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …

[HTML][HTML] Bioinformatics analyses determined the distinct CNS and peripheral surrogate biomarker candidates between two mouse models for progressive multiple …

S Omura, F Sato, NE Martinez, AM Park… - Frontiers in …, 2019 - frontiersin.org
Previously, we have established two distinct progressive multiple sclerosis (MS) models by
induction of experimental autoimmune encephalomyelitis (EAE) with myelin oligodendrocyte …

[HTML][HTML] Discovery of grey matter lesion-related immune genes for diagnostic prediction in multiple sclerosis

P Zhao, X Liu, Y Wang, X Zhang, H Wang, X Du, Z Du… - PeerJ, 2023 - peerj.com
Background Multiple sclerosis (MS) is a chronic debilitating disease characterized by
inflammatory demyelination of the central nervous system. Grey matter (GM) lesions have …

The analysis of dynamic gene expression patterns in peripheral blood of multiple sclerosis patients indicates possible diagnostic and prognostic biomarkers

R Razia, F Majeed, R Amin, S Mukhtar, K Mehmood… - Molecular …, 2022 - Elsevier
Introduction Among numerous invasive procedures for the research of biomarkers, blood-
based indicators are regarded as marginally non-invasive procedures in the diagnosis and …