[HTML][HTML] Identification of blood-derived candidate gene markers and a new 7-gene diagnostic model for multiple sclerosis
X Chen, H Hou, H Qiao, H Fan, T Zhao, M Dong - Biological Research, 2021 - Springer
Background Multiple sclerosis (MS) is a central nervous system disease with a high
disability rate. Modern molecular biology techniques have identified a number of key genes …
disability rate. Modern molecular biology techniques have identified a number of key genes …
[HTML][HTML] Identification of key genes associated with multiple sclerosis based on gene expression data from peripheral blood mononuclear cells
Z Shang, W Sun, M Zhang, L Xu, X Jia, R Zhang, S Fu - PeerJ, 2020 - peerj.com
The aim of this study was to identify the potential key candidate genes of multiple sclerosis
(MS) and uncover mechanisms in MS. We combined data from the microarray expression …
(MS) and uncover mechanisms in MS. We combined data from the microarray expression …
Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis
Multiple Sclerosis (MS) is a neurodegenerative autoimmune and organ-specific
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …
Microarray gene expression profiling analysis combined with bioinformatics in multiple sclerosis
M Liu, X Hou, P Zhang, Y Hao, Y Yang, X Wu… - Molecular biology …, 2013 - Springer
Multiple sclerosis (MS) is the most prevalent demyelinating disease and the principal cause
of neurological disability in young adults. Recent microarray gene expression profiling …
of neurological disability in young adults. Recent microarray gene expression profiling …
[HTML][HTML] Transcriptomic analysis of multiple sclerosis patient-derived monocytes by RNA-sequencing for candidate gene discovery
Multiple Sclerosis (MS) is an inflammatory disorder associated with immune abnormalities in
the Central Nervous System (CNS), including an abundance of monocytes in MS lesions …
the Central Nervous System (CNS), including an abundance of monocytes in MS lesions …
[HTML][HTML] Identification of key genes and microRNAs for multiple sclerosis using bioinformatics analysis
Z Xu, X Feng, W Zhu, M Qiu - Medicine, 2021 - journals.lww.com
To better understand the molecular mechanism underlying the pathogenesis of multiple
sclerosis (MS), we aimed to identify the key genes and microRNAs (miRNA) associated with …
sclerosis (MS), we aimed to identify the key genes and microRNAs (miRNA) associated with …
[HTML][HTML] Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis
Background The involvement of multiple genes and missing heritability, which are dominant
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …
[HTML][HTML] Bioinformatics analyses determined the distinct CNS and peripheral surrogate biomarker candidates between two mouse models for progressive multiple …
S Omura, F Sato, NE Martinez, AM Park… - Frontiers in …, 2019 - frontiersin.org
Previously, we have established two distinct progressive multiple sclerosis (MS) models by
induction of experimental autoimmune encephalomyelitis (EAE) with myelin oligodendrocyte …
induction of experimental autoimmune encephalomyelitis (EAE) with myelin oligodendrocyte …
[HTML][HTML] Discovery of grey matter lesion-related immune genes for diagnostic prediction in multiple sclerosis
P Zhao, X Liu, Y Wang, X Zhang, H Wang, X Du, Z Du… - PeerJ, 2023 - peerj.com
Background Multiple sclerosis (MS) is a chronic debilitating disease characterized by
inflammatory demyelination of the central nervous system. Grey matter (GM) lesions have …
inflammatory demyelination of the central nervous system. Grey matter (GM) lesions have …
The analysis of dynamic gene expression patterns in peripheral blood of multiple sclerosis patients indicates possible diagnostic and prognostic biomarkers
R Razia, F Majeed, R Amin, S Mukhtar, K Mehmood… - Molecular …, 2022 - Elsevier
Introduction Among numerous invasive procedures for the research of biomarkers, blood-
based indicators are regarded as marginally non-invasive procedures in the diagnosis and …
based indicators are regarded as marginally non-invasive procedures in the diagnosis and …