[HTML][HTML] Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles to treat PCOS

HS Park, E Cetin, H Siblini, J Seok, H Alkelani… - International Journal of …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is known as the most common endocrine disorder in
women. Previously, we suggested that human mesenchymal stem cells (MSCs) can reverse …

[HTML][HTML] Exosomes from mesenchymal stem/stromal cells: a new therapeutic paradigm

K Yin, S Wang, RC Zhao - Biomarker research, 2019 - Springer
Mesenchymal stem/stromal cells (MSCs) have been demonstrated to hold great potential for
the treatment of several diseases. Their therapeutic effects are largely mediated by …

[HTML][HTML] Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Mesenchymal stem cell-derived extracellular vesicles as therapeutics and as a drug delivery platform

G Baek, H Choi, Y Kim, HC Lee… - Stem cells translational …, 2019 - academic.oup.com
Mesenchymal stem cells (MSCs) are one of the most easily accessible stem cells that can be
obtained from various human tissues. They have raised considerable interests for their …

Focus on mesenchymal stem cell‐derived exosomes: opportunities and challenges in cell‐free therapy

L Cheng, K Zhang, S Wu, M Cui, T Xu - Stem cells international, 2017 - Wiley Online Library
Mesenchymal stem cells have been at the forefront of regenerative medicine for many years.
Exosomes, which are nanovesicles involved in intercellular communication and the …

[HTML][HTML] Exosomes derived from differentiated human ADMSC with the Schwann cell phenotype modulate peripheral nerve-related cellular functions

B Liu, Y Kong, W Shi, M Kuss, K Liao, G Hu, P Xiao… - Bioactive materials, 2022 - Elsevier
Peripheral nerve regeneration remains a significant clinical challenge due to the
unsatisfactory functional recovery and public health burden. Exosomes, especially those …

[HTML][HTML] Reproducible large-scale isolation of exosomes from adipose tissue-derived mesenchymal stem/stromal cells and their application in acute kidney injury

JH Lee, DH Ha, H Go, J Youn, H Kim, RC Jin… - International Journal of …, 2020 - mdpi.com
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …

[HTML][HTML] Human adipose mesenchymal stem cells modulate inflammation and angiogenesis through exosomes

JS Heo, S Kim - Scientific Reports, 2022 - nature.com
Stem cell-derived exosomes are efficient and safe therapeutic tools for transferring
endogenous biological cargo or functional biomolecules for regenerative medicine. The …

[HTML][HTML] Therapeutic features and updated clinical trials of mesenchymal stem cell (MSC)-derived exosomes

BC Lee, I Kang, KR Yu - Journal of clinical medicine, 2021 - mdpi.com
Identification of the immunomodulatory and regenerative properties of mesenchymal stem
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …

[HTML][HTML] A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine

S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …