Individuals who abuse alcohol often show exaggerated attentional bias (AB) towards
alcohol-related cues, which is thought to reflect reward conditioning processes. Rodent …

Recent brain–imaging studies revealed that the development and maintenance of alcohol
dependence is determined by a complex interaction of different neurotransmitter systems …

The value of rewards (natural rewards and drugs) is associated with dopamine increases in
the nucleus accumbens and varies as a function of context. The prefrontal cortex has been …

According to prevailing neurobiological theories of addiction, altered function in neural
reward circuitry is a central mechanism of alcohol dependence. Growing evidence …

Neuroadaptations following chronic exposure to alcohol are hypothesized to play important
roles in alcohol-induced alterations in behavior, in particular increased alcohol drinking and …

Introduction Alcohol‐associated cues activate both ventral and dorsal striatum in functional
brain imaging studies of heavy drinkers. In rodents, alcohol‐associated cues induce …

OBJECTIVE: Alcohol dependence may be associated with dysfunction of mesolimbic
circuitry, such that anticipation of nonalcoholic reward fails to activate the ventral striatum …

Rationale Animal experiments have provided evidence that the striatum and medial
prefrontal cortex play a predominant role in the acquisition and maintenance of drug …

Loss of flexible control over alcohol use may contribute to the development of alcohol use
disorders. An increased contribution of response habits to alcohol‐related behaviors may …

OBJECTIVE: Alcohol and other drugs of abuse stimulate dopamine release in the ventral
striatum, which includes the nucleus accumbens, a core region of the brain reward system …