Aims Hypoxic ischaemic encephalopathy (HIE) remains a significant cause of long term
neurodisability despite therapeutic hypothermia (TH). Infants with mild HIE, representing …

Importance Therapeutic hypothermia reduces risk of death and disability in infants with
moderate to severe hypoxic ischemic encephalopathy (HIE). Randomized clinical trials of …

Objective To compare the characteristics and outcomes of neonates with mild hypoxic-
ischemic encephalopathy (HIE) who received hypothermia versus standard care. Study …

Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

Background Therapeutic hypothermia reduces the risk of death, or moderate to severe
neurodevelopmental impairment (NDI) in term infants with hypoxic-ischemic …

Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled …

Background and Objective: There remains an unmet clinical need for markers that predict
outcomes in the hypothermia-treated (HT) infants with HIE. The aim of this meta-analysis …

Objective To determine whether moderate hypothermia after hypoxic-ischaemic
encephalopathy in neonates improves survival and neurological outcome at 18 months of …

Importance Hypoxic-ischemic encephalopathy (HIE) occurs in 1 to 8 per 1000 live births in
developed countries. Historically, the clinician has had little to offer neonates with HIE other …

Background Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many as 100,000
infants each year in China. Therapeutic hypothermia reduces HIE related mortality and long …