Synthesis and anti-Mycobacterium tuberculosis activity of imide-β-carboline and carbomethoxy-β-carboline derivatives
MA Lopes-Ortiz, MR Panice, EB de Melo… - European Journal of …, 2020 - Elsevier
A series of methyl β-carboline carboxylates (2a-g) and of imide-β-carboline derivatives
containing the phthalimide (4a-g), maleimide (5b, g) and succinimide (6b, e, g) moiety were …
containing the phthalimide (4a-g), maleimide (5b, g) and succinimide (6b, e, g) moiety were …
Synthesis and in vitro cytotoxic evaluation of 1, 3-bisubstituted and 1, 3, 9-trisubstituted β-carboline derivatives
R Cao, W Peng, H Chen, X Hou, H Guan… - European journal of …, 2005 - Elsevier
A series of novel 1, 3-bisubstituted and 1, 3, 9-trisubstituted β-carboline derivatives was
synthesized from the starting material l-tryptophan. Cytotoxic activities of these compounds …
synthesized from the starting material l-tryptophan. Cytotoxic activities of these compounds …
Synthesis and biological evaluation of a novel class of β-carboline derivatives
H Chen, P Gao, M Zhang, W Liao, J Zhang - New Journal of Chemistry, 2014 - pubs.rsc.org
In this study, several novel β-carboline derivatives, 1-(4-hydroxy-3-methoxyphenyl)-β-
carboline-3-carboxyl-Trp-Trp-AA-OBzl compounds, were designed and synthesized as …
carboline-3-carboxyl-Trp-Trp-AA-OBzl compounds, were designed and synthesized as …
An updates: Oxidative aromatization of THβC to β-carbolines and their application for the β-carboline alkaloids synthesis
This review is an informative and constructive resource for researchers interested in the
synthesis of β-carbolines. It provides a comprehensive overview of the various synthetic …
synthesis of β-carbolines. It provides a comprehensive overview of the various synthetic …
Design, synthesis and bio-evaluation of C-1 alkylated tetrahydro-β-carboline derivatives as novel antifungal lead compounds
R Singh, A Jaisingh, IK Maurya, DB Salunke - Bioorganic & Medicinal …, 2020 - Elsevier
The field of antifungal agent has become static and development of resistance by the
pathogen as well as limited clinical efficacy of marketed drugs demand the constant …
pathogen as well as limited clinical efficacy of marketed drugs demand the constant …
Synthesis of novel 1,2,3-triazole tethered 1,3-disubstituted β-carboline derivatives and their cytotoxic and antibacterial activities
P Salehi, K Babanezhad-Harikandei… - Medicinal Chemistry …, 2016 - Springer
In this paper new β-carboline derivatives possessing the 1, 2, 3-triazole ring at C-1
substituent were synthesized from L-tryptophan by Pictet–Spengler reaction followed by a …
substituent were synthesized from L-tryptophan by Pictet–Spengler reaction followed by a …
Metal-free 1, 3-dipolar cycloaddition approach towards the regioselective synthesis of β-carboline and isoxazole based molecular hybrids
Nature has nourished β-carboline and isoxazole derivatives as privileged scaffolds and
consequently they are ubiquitously found in alkaloids isolated from various sources …
consequently they are ubiquitously found in alkaloids isolated from various sources …
Synthesis and cytotoxic activities of β-carboline amino acid ester conjugates
M Zhao, L Bi, W Wang, C Wang, M Baudy-Floc'h… - Bioorganic & medicinal …, 2006 - Elsevier
β-Carboline represents a class of compounds with potent anti-tumor activity by intercalating
with DNA. To further enhance the cytotoxic potency and bioavailability of β-carboline, a …
with DNA. To further enhance the cytotoxic potency and bioavailability of β-carboline, a …
Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: synthesis and antimycobacterial evaluation
B Servusova-Vanaskova, O Jandourek, P Paterova… - …, 2015 - pubs.rsc.org
A series of alkylamino derivatives of N-benzylpyrazine-2-carboxamide was designed,
synthesized and assayed in vitro for their antimycobacterial, antibacterial, antifungal as well …
synthesized and assayed in vitro for their antimycobacterial, antibacterial, antifungal as well …
Benzannulation strategies for the synthesis of carbazoles, indolocarbazoles, benzocarbazoles, and carbolines
Nitrogen-containing π-excessive aromatic heterocycles, in particular, carbazoles,
indolocarbazoles, benzocarbazoles, and carbolines have been considered the fundamental …
indolocarbazoles, benzocarbazoles, and carbolines have been considered the fundamental …