A series of new β-carboline derivatives, bearing a benzylidine substituent at position-1, has
been prepared and evaluated in vitro against a panel of human cell lines. The N2 …

Infecting one-third of the world's inhabitants, Mycobacterium tuberculosis (MTB) is deemed a
serious public health concern.[1] Failure to follow the current regimen along with the HIV …

Three series of novel 1H-1, 2, 3-triazole-4-carboxamides: 1-aryl-5-alkyl/aryl-1H-1, 2, 3-
triazole-4-carboxamides, 1-aryl-5-amino-1H-1, 2, 3-triazole-4-carboxamides and 1, 2, 3 …

Four indole‐3‐carbaldehyde semicarbazone derivatives, 2‐((5‐bromo‐1H‐indol‐3‐yl)
methylene) hydrazinecarboxamide (1), 2‐((5‐chloro‐1H‐indol‐3‐yl) methylene) …

A series of β-carbolines possessing the aryl group at C-1 position has been synthesized
from tryptophan. The newly synthesized compounds were screened for their in vitro …

In the present study, a new series of β-carboline derivatives were synthesized and evaluated
for inhibition activity against both HIV-1 and HIV-2 strains. Among these reported analogues …

The increasing importance of enzyme mimics in organic synthesis inspired us to design a
novel biomimetic synthesis of β-carboline alkaloids directly from tryptophan and a second …

A series of novel 9-substituted β-carboline derivatives was synthesized from harmine and l-
tryptophan, respectively. Cytotoxic activities of these compounds in vitro were investigated …

To develop new potential antimycobacterial drugs, a series of pyrazinamide derivatives was
designed, synthesized and tested for their ability to inhibit the growth of selected …

Tetrahydro-γ-carbolines (THγ Cs) constitute one of the most important subtypes of indole
alkaloids. In addition to being substructures of natural products, these structural motifs and …