Characterization of HPV and host genome interactions in primary head and neck cancers
M Parfenov, CS Pedamallu… - Proceedings of the …, 2014 - National Acad Sciences
Previous studies have established that a subset of head and neck tumors contains human
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display …
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display …
Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric …
MJ Lace, JR Anson, JP Klussmann, DH Wang… - Journal of …, 2011 - Am Soc Microbiol
Many human papillomavirus (HPV)-positive high-grade lesions and cancers of the uterine
cervix harbor integrated HPV genomes expressing the E6 and E7 oncogenes from chimeric …
cervix harbor integrated HPV genomes expressing the E6 and E7 oncogenes from chimeric …
Human papillomavirus genome integration and head and neck cancer
LM Pinatti, HM Walline… - Journal of dental …, 2018 - journals.sagepub.com
We conducted a critical review of human papillomavirus (HPV) integration into the host
genome in oral/oropharyngeal cancer, reviewed the literature for HPV-induced cancers, and …
genome in oral/oropharyngeal cancer, reviewed the literature for HPV-induced cancers, and …
Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus
BJM Braakhuis, PJF Snijders… - Journal of the …, 2004 - academic.oup.com
Background: Transcriptionally active high-risk human papilloma viruses (HPVs), particularly
HPV type 16 (HPV16), are found in a subset of head and neck squamous-cell carcinomas …
HPV type 16 (HPV16), are found in a subset of head and neck squamous-cell carcinomas …
Mapping and analysis of HPV16 integration sites in a head and neck cancer cell line
CCR Ragin, SC Reshmi… - International journal of …, 2004 - Wiley Online Library
Human papillomavirus (HPV) is a circular double‐stranded DNA virus implicated in at least
90% of cervical and anogenital cancers and has been observed in approximately 20% of …
90% of cervical and anogenital cancers and has been observed in approximately 20% of …
Integration of human papillomavirus genomes in head and neck cancer: is it time to consider a paradigm shift?
IM Morgan, LJ DiNardo, B Windle - Viruses, 2017 - mdpi.com
Human papillomaviruses (HPV) are detected in 70–80% of oropharyngeal cancers in the
developed world, the incidence of which has reached epidemic proportions. The current …
developed world, the incidence of which has reached epidemic proportions. The current …
Genomic landscape of human papillomavirus–associated cancers
Recent next-generation sequencing studies have generated a comprehensive overview of
the genomic landscape of human papillomavirus (HPV)–associated cancers. This review …
the genomic landscape of human papillomavirus (HPV)–associated cancers. This review …
Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus
SJ Smeets, BJM Braakhuis, S Abbas, PJF Snijders… - Oncogene, 2006 - nature.com
Oncogene-expressing human papillomavirus type 16 (HPV16) is found in a subset of head
and neck squamous cell carcinomas (HNSCC). HPV16 drives carcinogenesis by …
and neck squamous cell carcinomas (HNSCC). HPV16 drives carcinogenesis by …
Intratumoral heterogeneity and clonal evolution induced by HPV integration
The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …
Pathogenesis of human papillomavirus‐associated mucosal disease
IJ Groves, N Coleman - The Journal of pathology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are a necessary cause of carcinoma of the cervix and other
mucosal epithelia. Key events in high‐risk HPV (HRHPV)‐associated neoplastic …
mucosal epithelia. Key events in high‐risk HPV (HRHPV)‐associated neoplastic …