Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization …

CY Chen, CY Yen, HR Wang, HP Yang, JY Tang… - Toxins, 2016 - mdpi.com
The development of drugs that selectively kill oral cancer cells but are less harmful to normal
cells still provide several challenges. In this study, the antioral cancer effects of tenuifolide B …

Tinospora sinensis (Lour.) Merr alkaloid rich extract induces colon cancer cell death via ROS mediated, mTOR dependent apoptosis pathway: “an in-vitro study”

S Badavenkatappa gari, VK Nelson… - … Medicine and Therapies, 2023 - Springer
Background Colorectal cancer (CRC) is the second most mortality rate causing disease after
lung cancer. Though there is a significant improvement in the treatment schedule offered to …

[HTML][HTML] Tinospora cordifolia (Thunb.) Miers (Giloy) inhibits oral cancer cells in a dose-dependent manner by inducing apoptosis and attenuating epithelial …

S Patil, H Ashi, J Hosmani, AY Almalki… - Saudi journal of …, 2021 - Elsevier
Abstract Background Tinospora cordifolia (Thunb.) Miers (Giloy) has been applied
successfully as an anti-inflammatory, anti-diabetic, and even as an anti-cancer agent. Yet, to …

Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells

GH Park, HM Song, SB Park, HJ Son, Y Um… - … and alternative medicine, 2018 - Springer
Abstract Background Because twigs of Cinnamomum cassia (TC) have been reported to
exert anti-cancer activity, the mechanistic study for TC's anti-cancer activity is required. Thus …

[Retracted] Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria‐Dependent Pathway

PY Tseng, WC Lu, MJ Hsieh, SY Chien… - BioMed Research …, 2014 - Wiley Online Library
Tanshinone IIA (Tan IIA), an active phytochemical in the dried root of Salvia miltiorrhiza
Bunge, has shown an antiproliferative activity on various human cancer cell lines including …

Cytotoxic Compounds from the Stems of Cinnamomum tenuifolium

RJ Lin, MJ Cheng, JC Huang, WL Lo… - Journal of natural …, 2009 - ACS Publications
Three new butanolides, tenuifolide A (1), isotenuifolide A (2), and tenuifolide B (3), a new
secobutanolide, secotenuifolide A (4), and one new sesquiterpenoid, tenuifolin (5), along …

Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways

J Li, X Xia, Y Ke, H Nie, MA Smith, X Zhu - Biochimica et Biophysica Acta …, 2007 - Elsevier
Trichosanthin (TCS), a traditional Chinese medicine, exerts antitumor activities by inducing
apoptosis in many different tumor cell lines. However, the mechanisms remain obscure. The …

A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and …

KC Rashmi, MH Raj, M Paul, KS Girish… - Chemico-biological …, 2019 - Elsevier
Approximately 15% of globally diagnosed breast cancers are designated as triple negative
breast cancer (TNBC). In this study, we investigated the effect of the natural compound, Bis …

Tetrandrine induces apoptosis via caspase‐8,‐9, and‐3 and poly (ADP ribose) polymerase dependent pathways and autophagy through beclin‐1/LC3‐I, II signaling …

FS Yu, CS Yu, JC Chen, JL Yang, HF Lu… - Environmental …, 2016 - Wiley Online Library
Tetrandrine is a bisbenzylisoquinoline alkaloid that was found in the Radix Stephania
tetrandra S Moore. It had been reported to induce cytotoxic effects on many human cancer …

Stellettin B-induced oral cancer cell death via endoplasmic reticulum stress–mitochondrial apoptotic and autophagic signaling pathway

TJ Kuo, YH Jean, PC Shih, SY Cheng, HM Kuo… - International Journal of …, 2022 - mdpi.com
Oral squamous cell carcinoma (OSCC) affects tens of thousands of people worldwide.
Despite advances in cancer treatment, the 5-year survival rate of patients with late-stage …