Polymorphisms of the insulin receptor and the insulin receptor substrates genes in polycystic ovary syndrome: a Mendelian randomization meta-analysis
A Ioannidis, E Ikonomi, NL Dimou, L Douma… - Molecular genetics and …, 2010 - Elsevier
Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown aetiology
which is considered to be the most common endocrine disorder in women of reproductive …
which is considered to be the most common endocrine disorder in women of reproductive …
Associations of insulin receptor and insulin receptor substrates genetic polymorphisms with polycystic ovary syndrome: A systematic review and meta‐analysis
X Shi, X Xie, Y Jia, S Li - Journal of Obstetrics and Gynaecology …, 2016 - Wiley Online Library
Aim Recently, the roles of insulin receptor (INSR) and insulin receptor substrate (IRS)
polymorphisms in polycystic ovary syndrome (PCOS) have been extensively studied, with …
polymorphisms in polycystic ovary syndrome (PCOS) have been extensively studied, with …
[HTML][HTML] The Association between Polymorphism of INSR and Polycystic Ovary Syndrome: A Meta-Analysis
C Feng, PP Lv, TT Yu, M Jin, JM Shen, X Wang… - International journal of …, 2015 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorder.
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …
[HTML][HTML] Insulin receptor substrate-1 (IRS-1) rs1801278G> A polymorphism is associated with polycystic ovary syndrome susceptibility: a meta-analysis
W Tang, Y Wang, H Jiang, C Liu, C Dong… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
The correlation between insulin receptor substrate-1 (IRS-1) rs1801278G> A polymorphism
and polycystic ovary syndrome (PCOS) has been widely studied. However, the results of …
and polycystic ovary syndrome (PCOS) has been widely studied. However, the results of …
[HTML][HTML] Association of insulin receptor genetic variants with polycystic ovary syndrome in a population of women from Central Europe
FA Hanzu, S Radian, R Attaoua, S Ait-El-Mkadem… - Fertility and sterility, 2010 - Elsevier
To assess the role of the insulin receptor gene in polycystic ovary syndrome (PCOS) we
performed a case-control study in a female population (n= 226) from Central Europe by …
performed a case-control study in a female population (n= 226) from Central Europe by …
Relationship of insulin receptor substrate-1 and-2 genotypes to phenotypic features of polycystic ovary syndrome
DA Ehrmann, X Tang, I Yoshiuchi… - The Journal of Clinical …, 2002 - academic.oup.com
Insulin resistance is a key component in the pathogenesis of polycystic ovary syndrome
(PCOS) and type 2 diabetes. Polymorphisms in the genes encoding the insulin receptor …
(PCOS) and type 2 diabetes. Polymorphisms in the genes encoding the insulin receptor …
[HTML][HTML] Replication of association of a novel insulin receptor gene polymorphism with polycystic ovary syndrome
OBJECTIVE: To evaluate association with polycystic ovary syndrome (PCOS) of 295 variants
in 39 genes central to metabolic insulin signaling and glycogen synthase kinase 3β (GSK …
in 39 genes central to metabolic insulin signaling and glycogen synthase kinase 3β (GSK …
[HTML][HTML] AC/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome
S Siegel, W Futterweit, TF Davies, ES Concepcion… - Fertility and sterility, 2002 - Elsevier
OBJECTIVE: To examine whether the insulin receptor (INSR) gene contributes to genetic
susceptibility to the polycystic ovary syndrome (PCOS). DESIGN: Case–control study …
susceptibility to the polycystic ovary syndrome (PCOS). DESIGN: Case–control study …
Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis
Y Ruan, J Ma, X Xie - Endocrine journal, 2012 - jstage.jst.go.jp
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing
210006, China abstract. Insulin resistance (IR) plays an important role in the pathogenesis …
210006, China abstract. Insulin resistance (IR) plays an important role in the pathogenesis …
Genetic polymorphisms of INS, INSR and IRS-1 genes are not associated with polycystic ovary syndrome in Croatian women
Sažetak Obesity and insulin resistance is a common finding in patients with polycystic ovary
syndrome (PCOS). Significant number of PCOS women experience insulin resistance that is …
syndrome (PCOS). Significant number of PCOS women experience insulin resistance that is …
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