Emerging potential of stimulus-responsive nanosized anticancer drug delivery systems for systemic applications

HB Ruttala, T Ramasamy, T Madeshwaran… - Archives of pharmacal …, 2018 - Springer
The development of novel drug delivery systems based on well-defined polymer
therapeutics has led to significant improvements in the treatment of multiple disorders …

pH-responsive high stability polymeric nanoparticles for targeted delivery of anticancer therapeutics

L Palanikumar, S Al-Hosani, M Kalmouni… - Communications …, 2020 - nature.com
The practical application of nanoparticles (NPs) as chemotherapeutic drug delivery systems
is often hampered by issues such as poor circulation stability and targeting inefficiency …

[HTML][HTML] Polymeric nanocarriers as stimuli-responsive systems for targeted tumor (cancer) therapy: Recent advances in drug delivery

M Alsehli - Saudi Pharmaceutical Journal, 2020 - Elsevier
In the last decade, considerable attention has been devoted to the use of biodegradable
polymeric materials as potential drug delivery carriers. However, bioavailability and drug …

pH-responsive nanocarriers in cancer therapy

NM AlSawaftah, NS Awad, WG Pitt, GA Husseini - Polymers, 2022 - mdpi.com
A number of promising nano-sized particles (nanoparticles) have been developed to
conquer the limitations of conventional chemotherapy. One of the most promising methods is …

Strategies To Design and Synthesize Polymer‐Based Stimuli‐Responsive Drug‐Delivery Nanosystems

X Qin, Y Li - ChemBioChem, 2020 - Wiley Online Library
The emergence and development of nanomedicine have alleviated problems existing in
traditional chemotherapy drugs, such as short lifetime, concomitant side effects, and weak …

Stimuli-responsive polymer-based nanosystems for cancer theranostics

D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

pH‐Sensitive stimulus‐responsive nanocarriers for targeted delivery of therapeutic agents

M Karimi, M Eslami… - Wiley …, 2016 - Wiley Online Library
In recent years miscellaneous smart micro/nanosystems that respond to various exogenous/
endogenous stimuli including temperature, magnetic/electric field, mechanical force …

Tumor microenvironment-responsive nanoparticle delivery of chemotherapy for enhanced selective cellular uptake and transportation within tumor

WC Huang, SH Chen, WH Chiang, CW Huang… - …, 2016 - ACS Publications
A novel drug delivery strategy featured with enhanced uptake of nanoparticles (NPs) by
targeted tumor cells and subsequent intratumoral cellular hitchhiking of chemotherapy to …

pH-Activatable Charge-Reversal Polymer-Based Nanocarriers for Targeted Delivery of Antihepatoma Compound

S Chen, FD Zhu, ZQ Nie, CT Yang, JM Yang, J He… - Langmuir, 2023 - ACS Publications
Chemotherapy is one of the available cancer treatments which has been successfully
employed to prolong the survival of cancer patients. However, it remains a major challenge …

pH‐responsive polymer nanoparticles for drug delivery

N Deirram, C Zhang, SS Kermaniyan… - Macromolecular …, 2019 - Wiley Online Library
Stimuli‐responsive nanoparticles have the potential to improve the delivery of therapeutics
to a specific cell or region within the body. There are many stimuli that have shown potential …