[HTML][HTML] Novel diagnostic biomarkers related to immune infiltration in Parkinson's disease by bioinformatics analysis

P Zhang, L Zhao, H Li, J Shen, H Li… - Frontiers in Neuroscience, 2023 - frontiersin.org
Background Parkinson's disease (PD) is Pengfei Zhang Liwen Zhao Pengfei Zhang Liwen
Zhao a common neurological disorder involving a complex relationship with immune …

[HTML][HTML] Identification of immune-related hub genes in Parkinson's disease

L Chen, Y Wang, J Huang, B Hu, W Huang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Parkinson's disease (PD) is a common, age-related, and progressive
neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an …

Identifying the hub gene and immune infiltration of Parkinson's disease using bioinformatical methods

SH Liu, YL Wang, SM Jiang, XJ Wan, JH Yan, CF Liu - Brain Research, 2022 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disorder that affects
1%–2% of the population over 60 years old. Immune response dysfunction in the brain …

[HTML][HTML] Integrative analysis of potential biomarkers and immune cell infiltration in Parkinson's disease

X Chen, W Cao, Y Zhuang, S Chen, X Li - Brain Research Bulletin, 2021 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disease in the
elderly population. However, there are no reliable diagnostic biomarkers for PD, and the …

[HTML][HTML] Identification of potential immune-related hub genes in Parkinson's disease based on machine learning and development and validation of a diagnostic …

G Xin, J Niu, Q Tian, Y Fu, L Chen, T Yi, K Tian, X Sun… - PloS One, 2023 - journals.plos.org
Background Parkinson's disease is the second most common neurodegenerative disease in
the world. However, current diagnostic methods are still limited, and available treatments …

[HTML][HTML] Integrative analysis of gene expression profiles of substantia nigra identifies potential diagnosis biomarkers in Parkinson's disease

J Huang, B Li, H Wei, C Li, C Liu, H Mi, S Chen - Scientific Reports, 2024 - nature.com
Parkinson's disease (PD) is a progressive neurodegenerative disease whose etiology is
attributed to development of Lewy bodies and degeneration of dopaminergic neurons in the …

Integrated Bioinformatics Analysis for Revealing CBL is a Potential Diagnosing Biomarker and Related Immune Infiltration in Parkinson's Disease

Y Chen, Y Tu, G Yan, X Ji, S Chen, C Niu… - International Journal of …, 2024 - Taylor & Francis
Purpose There is growing evidence that the immune system plays an important role in the
progression of Parkinson's disease, the second most common neurodegenerative disorder …

[HTML][HTML] Immune profiling of Parkinson's disease revealed its association with a subset of infiltrating cells and signature genes

X Zhang, Z Shao, S Xu, Q Liu, C Liu, Y Luo… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is an age-related and second most common neurodegenerative
disorder. In recent years, increasing evidence revealed that peripheral immune cells might …

[HTML][HTML] Significant difference of immune cell fractions and their correlations with differential expression genes in Parkinson's disease

Y Huang, H Liu, J Hu, C Han, Z Zhong… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is the second most neurodegenerative disease in the world. T cell
infiltration in the central nervous system (CNS) has provided insights that the peripheral …

Bioinformatics gene analysis for potential biomarkers and therapeutic targets of Parkinson's disease based on neutrophil extracellular traps

Q Wang, Y Gu, J Chen, X Liu, C Xie… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction Neutrophil extracellular traps (NETs) provide key innate immune mechanisms,
and studies have shown innate immunity and adaptive immunity are directly linked to …