Simultaneous quantification of eleven short-chain fatty acids by derivatization and solid phase microextraction-gas chromatography tandem mass spectrometry

Z Fu, Q Jia, H Zhang, L Kang, X Sun, M Zhang… - … of Chromatography A, 2022 - Elsevier
As metabolites of the gut microbiome, short-chain fatty acids (SCFAs) played an important
role in the diagnosis of the metabolic diseases. Because of the high polarity, high volatility …

An in situ extraction and derivatization method for rapid analysis of short-chain fatty acids in rat fecal samples by gas chromatography tandem mass spectrometry

NH Park, MS Kim, W Lee, ME Lee, J Hong - Analytical Methods, 2017 - pubs.rsc.org
Short-chain fatty acids (SCFAs) are major products of gut microbial fermentation and
changes in their levels in a biological system reflect the progress of various diseases …

A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples

S Zhang, H Wang, MJ Zhu - Talanta, 2019 - Elsevier
Gut microbiota and their major metabolites, short-chain fatty acids (SCFAs), are recognized
as important players in gut homeostasis and metabolic disease occurance. A convenient …

A gas chromatography mass spectrometry-based method for the quantification of short chain fatty acids

JK Rohde, MM Fuh, I Evangelakos, MJ Pauly… - Metabolites, 2022 - mdpi.com
Short Chain Fatty Acids (SCFAs) are produced by the gut microbiota and are present in
varying concentrations in the intestinal lumen, in feces but also in the circulatory system. By …

Optimization and validation of direct gas chromatography-mass spectrometry method for simultaneous quantification of ten short-chain fatty acids in rat feces

JH Zhu, Q Mao, SY Wang, H Liu, SS Zhou… - … of Chromatography A, 2022 - Elsevier
Short-chain fatty acids (SCFAs) play key roles in maintaining health and treating disease.
Quantification of important fecal SCFAs is necessary to facilitate the clarification of their …

Analytical factors for eight short-chain fatty acid analyses in mouse feces through headspace solid-phase microextraction–triple quadrupole gas chromatography …

S Kang, J Yun, HY Park, JE Lee - Analytical and Bioanalytical Chemistry, 2023 - Springer
This study developed a method for quantifying eight short-chain fatty acids (SCFAs) in
mouse fecal samples using solid-phase microextraction (SPME) coupled with triple …

A rapid and convenient derivatization method for quantitation of short‐chain fatty acids in human feces by ultra‐performance liquid chromatography/tandem mass …

H Fu, Q Zhang, X Huang, Z Ma, X Zheng… - Rapid …, 2020 - Wiley Online Library
Rationale Short‐chain fatty acids (SCFAs) are associated with intestinal microbiota and
diseases in humans. SCFAs have a low response in mass spectrometry, and in order to …

Chemical derivatization-based LC–MS/MS method for quantitation of gut microbial short-chain fatty acids

WS Song, HG Park, SM Kim, SH Jo, BG Kim… - Journal of Industrial and …, 2020 - Elsevier
Short chain fatty acids (SCFAs) are end products of fermentation by anaerobic gut
microbiota. They can be used as beneficial metabolites to regulate the host's physiological …

Simultaneous quantification of straight-chain and branched-chain short chain fatty acids by gas chromatography mass spectrometry

L He, MAI Prodhan, F Yuan, X Yin… - … of Chromatography B, 2018 - Elsevier
Biomedical research in areas such as metabolic disorders, neuromodulatory, and
immunomodulatory conditions involves lipid metabolism and demands a reliable and …

An improved method to quantify short-chain fatty acids in biological samples using gas chromatography–mass spectrometry

KS Kim, Y Lee, W Chae, JY Cho - Metabolites, 2022 - mdpi.com
Gut microbial metabolites, short-chain fatty acids (SCFAs), are found at multiple locations in
the host body and are identified as important metabolites in gut microbiome-associated …