Immune Response to Yersinia Outer Proteins and Other Yersinia pestis Antigens after Experimental Plague Infection in Mice

GE Benner, GP Andrews, WR Byrne… - Infection and …, 1999 - Am Soc Microbiol
There is limited information concerning the nature and extent of the immune response to the
virulence determinants of Yersinia pestis during the course of plague infection. In this study …

Immune response to plasmid-and chromosome-encoded Yersinia antigens

G Mazza, AE Karu, DT Kingsbury - Infection and immunity, 1985 - Am Soc Microbiol
The immune response of humans and mice to temperature-specific, plasmid-or chromosome-
encoded proteins of yersinia pestis and Yersinia enterocolitica was investigated by sodium …

Protective Efficacy of RecombinantYersinia Outer Proteins against Bubonic Plague Caused by Encapsulated and Nonencapsulated Yersinia pestis

GP Andrews, ST Strachan, GE Benner… - Infection and …, 1999 - Am Soc Microbiol
To evaluate the role of Yersinia outer proteins (Yops) in conferring protective immunity
against plague, six yop loci from Yersinia pestis were individually amplified by PCR, cloned …

Role of immune response in Yersinia pestis infection

A Amedei, E Niccolai, L Marino, MM D'Elios - The Journal of Infection in …, 2011 - jidc.org
Yersinia pestis (Y. Pestis) is an infamous pathogen causing plague pandemics throughout
history and is a selected agent of bioterrorism threatening public health. Y. pestis was first …

Pathogenesis of Yersinia pestis Infection in BALB/c Mice: Effects on Host Macrophages and Neutrophils

RA Lukaszewski, DJ Kenny, R Taylor… - Infection and …, 2005 - Am Soc Microbiol
The pathogenesis of infection with Yersinia pestis, the causative agent of plague, was
examined following subcutaneous infection of BALB/c mice with a fully virulent strain …

Characterization of the lipopolysaccharide of Yersinia pestis

JL Prior, PG Hitchen, DE Williamson, AJ Reason… - Microbial …, 2001 - Elsevier
Lipopolysaccharide (LPS) extracted from eight strains of Yersinia pestis, which had been
cultured at 28 or 37° C, reacted equally well, in Western blots, with four monoclonal …

Regions of Yersinia pestis V antigen that contribute to protection against plague identified by passive and active immunization

J Hill, SE Leary, KF Griffin, ED Williamson… - Infection and …, 1997 - Am Soc Microbiol
V antigen of Yersinia pestis is a multifunctional protein that has been implicated as a
protective antigen, a virulence factor, and a regulatory protein. A series of V-antigen …

Plague virulence antigens from Yersinia enterocolitica

PB Carter, RJ Zahorchak, RR Brubaker - Infection and immunity, 1980 - Am Soc Microbiol
The virulence of Yersinia enterocolitica, biotype 2, serotype O: 8, in mice is related to its
ability to produce plague V and W antigens. V and W antigens in Y. enterocolitica are shown …

Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine

TE Erova, JA Rosenzweig, J Sha… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
Plague caused by Yersinia pestis manifests itself in bubonic, septicemic, and pneumonic
forms. Although the US Food and Drug Administration recently approved levofloxacin, there …

Neutralization of Yersinia pestis-mediated macrophage cytotoxicity by anti-LcrV antibodies and its correlation with protective immunity in a mouse model of bubonic …

A Zauberman, S Cohen, Y Levy, G Halperin, S Lazar… - Vaccine, 2008 - Elsevier
Plague is a life-threatening disease caused by Yersinia pestis, for which effective-licensed
vaccines and reliable predictors of in vivo immunity are lacking. V antigen (LcrV) is a major …