Grapefruit juice improves glucose intolerance in streptozotocin-induced diabetes by suppressing hepatic gluconeogenesis

JA Hayanga, SP Ngubane, AN Murunga… - European journal of …, 2016 - Springer
Purpose Hypoglycemic effects of grapefruit juice (GFJ) are widely recognized, but the
mechanism (s) by which GFJ lowers blood glucose levels have not previously been …

[PDF][PDF] Grapefruit juice improves glycemic control but exacerbates metformin-induced lactic acidosis in non-diabetic rats

PM Owira, JA Ojewole - Methods Find Exp Clin Pharmacol, 2009 - researchgate.net
Recent clinical studies have indicated that grapefruit juice (GFJ) improves insulin resistance
and reduces weight gain in humans. The effect of GFJ on glucose tolerance and metformin …

Fisetin improves glucose homeostasis through the inhibition of gluconeogenic enzymes in hepatic tissues of streptozotocin induced diabetic rats

GS Prasath, SI Pillai, SP Subramanian - European journal of pharmacology, 2014 - Elsevier
Liver plays a vital role in blood glucose homeostasis. Recent studies have provided
considerable evidence that hepatic glucose production (HGP) plays an important role in the …

Grapefruit derived flavonoid naringin improves ketoacidosis and lipid peroxidation in type 1 diabetes rat model

AN Murunga, DO Miruka, C Driver, FS Nkomo… - PLoS …, 2016 - journals.plos.org
Background Hypoglycemic effects of grapefruit juice are well known but the effects of
naringin, its main flavonoid on glucose intolerance and metabolic complications in type 1 …

Effect of feeding grape pomace on selected metabolic parameters associated with high fructose feeding in growing Sprague–Dawley rats

RC Khanal, LR Howard, TJ Rogers… - Journal of Medicinal …, 2011 - liebertpub.com
The effect of feeding grape pomace on certain metabolic parameters associated with high
fructose (HF) feeding was studied. Forty male growing Sprague–Dawley rats were randomly …

Grape pomace and grape pomace extract improve insulin signaling in high-fat-fructose fed rat-induced metabolic syndrome

CR Lanzi, DJ Perdicaro, A Antoniolli, AR Fontana… - Food & function, 2016 - pubs.rsc.org
In this study the effect of diet supplementation with grape pomace (GP) and grape pomace
extract (GPE) on insulin sensitive tissues (adipose, liver and muscle) was evaluated in an …

Consumption of clarified grapefruit juice ameliorates high-fat diet induced insulin resistance and weight gain in mice

R Chudnovskiy, A Thompson, K Tharp, M Hellerstein… - PLoS …, 2014 - journals.plos.org
To determine the metabolic effects of grapefruit juice consumption we established a model
in which C57Bl/6 mice drank 25–50% sweetened GFJ, clarified of larger insoluble particles …

[HTML][HTML] Grape pomace aqueous extract (GPE) prevents high fat diet-induced diabetes and attenuates systemic inflammation

H Li, J Parry, S Weeda, S Ren, TW Castonguay… - Food and Nutrition …, 2016 - scirp.org
Diabetes mellitus is a group of metabolic syndromes with a hallmark of hyperglycemia.
Serious long-term complications from diabetes are a major cause of hospitalization and …

[PDF][PDF] Hypoglycemic and hypolipidemic effects of grapefruit juice in diabetic rats

WMA Hamed, KY Abid, SAU Al-Amin - Tikrit J. Pure Sci, 2008 - iasj.net
The goal of this study was to investigate the hypoglycemic effect and the hypolipidemic
changes following the ingestion of an extract of grapefruit juice, which was fed intra …

Antioxidant rich grape pomace extract suppresses postprandial hyperglycemia in diabetic mice by specifically inhibiting alpha-glucosidase

S Hogan, L Zhang, J Li, S Sun, C Canning… - Nutrition & metabolism, 2010 - Springer
Background Postprandial hyperglycemia is an early defect of type 2 diabetes and one of
primary anti-diabetic targets. Treatment of postprandial hyperglycemia can be achieved by …