We have characterized the receptor (s) mediating contraction and relaxation produced by
tachykinins in the rabbit isolated jugular vein. The tachykinin NK1 receptor-selective …

Tissue (glandular) kallikrein is a serin-protease able to release bradykinin (BK) and Lys-BK
from both high molecular weight (HMW) and low molecular weight (LMW) kininogens …

A family of peptides that shares a common C-terminal sequence (Phe-X-Gly-Leu-MetNH 2)
exists in mammalian and non-mammalian species. In mammals, three of these peptides …

Offers a state-of-the-art review by international experts on all aspects of tachykinin receptors,
including neuropeptide/peptide and G-protein-linked receptors in general. It covers the …

In a recent article in RPTH, Gangnus and Burckhardt present the preanalytic variables that
need be considered for the reliable measurement of bradykinin (BK). 1 This topic has been …

The tachykinin NK1 receptor is widely distributed in both the central and peripheral nervous
system. In the CNS, NK1 receptors have been implicated in various behavioural responses …

We have investigated the effects of angiotensin-converting enzyme (ACE) inhibitors on
intracellular Ca2+ levels in human cultured endothelial cells and on endothelial autacoid …

Throughout the past decade, major advances have been made in our understanding of the
biology of the mammalian tachykinin neuropeptides. It is now well established that …

Vasoactive neuropeptides including substance P and calcitonin gene-related peptide
(CGRP) are localised in sensory nerves which innervate blood vessels. These are the major …

Kinin B1 and B2 receptors play an essential role in inflammatory process and cardiovascular
homeostasis. The present study investigated the vascular reactivity and nitric oxide (NO) …