Expression and prognostic signatures of m6A-related lncRNAs in hepatocellular carcinoma

K Hao, J Li, Y Zhang, W Zhao, X Chen, J Xu… - Journal of Cancer …, 2023 - Springer
Abstract Background N6-methyladenosine (m6A) is a common modification and plays an
important role in various biological processes, but m6A-related lncRNA functions in …

The m6A-related gene signature stratifies poor prognosis patients and characterizes immunosuppressive microenvironment in hepatocellular carcinoma

E Ma, J Li, C Shen, Y Gu, X Zhang, L Li, J Zhao… - Frontiers in …, 2023 - frontiersin.org
Background N6-methyladenosine (m6A) is the most abundant epitranscriptomic modification
of RNA, which can affect RNA metabolism and protein translation. The m6A modification …

Comprehensive analysis of N6-methyladenosine-related long non-coding RNAs and immune cell infiltration in hepatocellular carcinoma

ZL Yu, ZM Zhu - Bioengineered, 2021 - Taylor & Francis
We aimed to illustrate the influence of N6-methyladenosine (m6A) long non-coding RNAs
(lncRNAs) and immune cell infiltration in hepatocellular carcinoma (HCC). The relationship …

An m6A-related prognostic biomarker associated with the hepatocellular carcinoma immune microenvironment

Y Du, Y Ma, Q Zhu, T Liu, Y Jiao, P Yuan… - Frontiers in …, 2021 - frontiersin.org
Background: N6-methyladenosine (m6A) is related to the progression of multiple cancers.
However, the underlying influences of m6A-associated genes on the tumor immune …

Identification of m6A-and ferroptosis-related lncRNA signature for predicting immune efficacy in hepatocellular carcinoma

H Xie, M Shi, Y Liu, C Cheng, L Song, Z Ding… - Frontiers in …, 2022 - frontiersin.org
Background N6-methyladenosine (m6A) methylation and ferroptosis assist long noncoding
RNAs (lncRNAs) in promoting immune escape in hepatocellular carcinoma (HCC) …

A m6A regulators-related classifier for prognosis and tumor microenvironment characterization in hepatocellular carcinoma

S Xu, Y Zhang, Y Yang, K Dong, H Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Increasing evidence have highlighted the biological significance of mRNA N6-
methyladenosine (m6A) modification in regulating tumorigenicity and progression. However …

Prognostic risk model and tumor immune environment modulation of m5C-related LncRNAs in pancreatic ductal adenocarcinoma

H Yuan, J Liu, L Zhao, P Wu, G Chen, Q Chen… - Frontiers in …, 2021 - frontiersin.org
RNA methylation modification is a key process in epigenetics that regulates
posttranscriptional gene expression. With advances in next-generation sequencing …

[HTML][HTML] Use of 6 m6A-relevant lncRNA genes as prognostic markers of primary liver hepatocellular carcinoma based on TCGA database

XL Zhu, Q Li, J Shen, L Shan, ED Zuo… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background Hepatocellular carcinoma (HCC) is diagnosed at the middle and advanced
stages, negating radical treatment. Identifying specific and effective prognostic HCC …

Comprehensive analysis of basement membrane and immune checkpoint related lncRNA and its prognostic value in hepatocellular carcinoma via machine learning

Z Jin, Y Meng, M Wang, D Chen, M Zhu, Y Huang… - Heliyon, 2023 - cell.com
Background Hepatocellular carcinoma (HCC), which is characterized by its high
malignancy, generally exhibits poor response to immunotherapy. As part of the tumor …

Construction and validation of an immune-related LncRNA prognostic model for hepatocellular carcinoma

C Xin, B Huang, M Chen, H Yan, K Zhu, L Chen… - Cytokine, 2022 - Elsevier
Herein, based on mRNA data from TCGA database, hepatocellular carcinoma (HCC)
samples were subjected to a single-sample Gene Set Enrichment Analysis (ssGSEA). Then …