Tumor invasion, angiogenesis and metastasis involve secretion of proteolytic enzymes and
cell migration into blood vessels. Tumor cells are capable of degrading the extracellular …

Genistein has been reported to be a natural chemopreventive in several types of human
cancer. In our prior study, soy isoflavones were shown to induce cell cycle arrest and …

The studies presented were conducted to assess the effect of the soy isoflavone genistein
on proliferation of estrogen-independent human breast cancer cells (MDA-MB-231) in vitro …

Two dietary soybean isoflavones, genistein and daidzein, were studied for the inhibition of
lung metastasis induced by B16F‐10 melanoma cells in C57BL/6 mice. The isoflavone …

To investigate the effects soy isoflavones in established cancers, the role of genistein,
daidzein, and combined soy isoflavones was studied on progression of subcutaneous …

Consumption of soy products has been linked to a reduced mortality and morbidity from a
number of cancers. Genistein, one of the principal soy isoflavones, has been shown to …

Angiogenesis is an essential process involved in the development and progression of
prostate cancer. Vascular endothelial growth factor (VEGF) is hypothesized to be a critical …

Previously our laboratory has shown that the soy isoflavone, genistein, stimulates growth of
human breast cancer (MCF-7) cells in vivo and in vitro. In this study, the dose-response …

The isoflavonoid genistein, the aglycone of the heteroside genistin, possesses preventive
effect on coronary heart disease and osteoporosis, antioxidant, anthelmintic, antineoplastic …

Genistein, a natural isoflavonoid phyto-oestrogen, inhibits the tyrosine kinase activity of
growth factor receptors and oncogene products, as well as the in vitro growth of some …