Bezafibrate improves hypertension and insulin sensitivity in humans

JI Kim, T Tsujino, Y Fujioka, K Saito… - Hypertension …, 2003 - jstage.jst.go.jp
We examined cellular membrane fatty acid composition and insulin sensitivity in patients
with mild essential hypertension and hyperlipidemia, and investigated whether bezafibrate …

Effects of bezafibrate on insulin secretion and peripheral insulin sensitivity in hyperlipidemic patients with and without diabetes

G Riccardi, S Genovese, G Saldalamacchia, L Patti… - Atherosclerosis, 1989 - Elsevier
Although it has been reported that bezafibrate influences carbohydrate metabolism, this
possibility has never been properly evaluated in a controlled clinical trial. In this study we …

Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia

IJ Jonkers, FH de Man, A van der Laarse… - Journal of …, 2001 - journals.lww.com
Objective In hypertriglyceridemic patients, hypertension occurs frequently and may be
associated with hyperinsulinemia and elevated plasma levels of free fatty acids (FFA) …

Bezafibrate: an update of its pharmacology and use in the management of dyslipidaemia

KL Goa, LB Barradell, GL Plosker - Drugs, 1996 - Springer
Synopsis The lipid-modifying profile of bezafibrate is characterised by marked decreases in
elevated triglyceride levels, increases in high density lipoprotein (HDL) cholesterol levels …

Double‐blind Placebo‐controlled Study of the Effects of Bezafibrate on Blood Lipids, Lipoproteins, and Fibrinogen in Hyperlipidaemic Type 1 Diabetes Mellitus

PH Winocour, PN Durrington, D Bhatnagar… - Diabetic …, 1990 - Wiley Online Library
The effects of bezafibrate 400 mg day− 1 or placebo administered for 3 months, were
compared in 36 patients with stable Type 1 diabetes and hypercholesterolaemia and/or …

Effects of bezafibrate on insulin sensitivity and glucose tolerance in subjects with combined hyperlipidemia

P Karhapää, M Uusitupa, E Voutilainen… - Clinical …, 1992 - Wiley Online Library
To investigate whether the lowering of triglyceride levels has beneficial effects on glucose
metabolism, we studied 13 nondiabetic men with combined hyperlipidemia (phenotype IIB) …

Effect of bezafibrate on metabolic profiles in non-insulin-dependent diabetes mellitus

K Alberti, R Jones, MF Laker, ABM Swai… - Journal of …, 1990 - journals.lww.com
Non-insuiin-dependent diabetes mellitus (NIDDM) is characterized by hyperglycemia
secondary to increased hepatic glucose output and impaired extrahepatic insulin sensitivity …

Improvement of glucose tolerance by bezafibrate in non-obese patients with hyperlipidemia and impaired glucose tolerance

I Inoue, K Takahashi, S Katayama, S Akabane… - Diabetes research and …, 1994 - Elsevier
Glucose intolerance or diabetes mellitus, hyperlipidemia, obesity and hypertension may
have a close interrelation based on insulin resistance. We selected 28 impaired glucose …

Bezafibrate retard in type II diabetic patients: effects on hemostasis and glucose homeostasis

DP Mikhailidis, S Mathur, MA Barradas… - Journal of …, 1990 - journals.lww.com
A double-blind, placebo-controlled trial assessed the effect of a slow-release formulation of
bezafibrate (Bezalip Mono, 400 mg daily for 3 months) on lipid profile, glucose homeostasis …

Bezafibrate retard in patients with insulin-dependent diabetes: effect on serum lipoproteins, fibrinogen, and glycemic control

PN Durrington, PH Winocour… - Journal of cardiovascular …, 1990 - journals.lww.com
The effects of a sustained-release preparation of bezafibrate (Bezalip Mono) 400 mg once
daily and placebo administered for 3 months were compared in 36 patients with stable type …