Pertussis toxin (PT) is a multisubunit protein toxin secreted by Bordetella pertussis, the
bacterial agent of the disease pertussis or whooping cough. PT in detoxified form is a …

Pertussis, caused by respiratory tract infection with the bacterial pathogen Bordetella
pertussis, has long been considered to be a toxin-mediated disease. Bacteria adhere and …

B. pertussis is a human-specific pathogen and the causative agent of whooping cough. The
ongoing resurgence in pertussis incidence in high income countries is likely due to faster …

Bordetella pertussis produces several toxins that affect host-pathogen interactions. Of these,
the major toxins that contribute to pertussis infection and disease are pertussis toxin …

Pertussis toxin and adenylate cyclase toxin are two important virulence factors of Bordetella
pertussis, the bacterial cause of the respiratory disease pertussis or whooping cough. In …

Besides the typical whooping cough syndrome, infection with Bordetella pertussis or
immunization with whole-cell vaccines can result in a wide variety of physiological …

Pertussis toxin, produced and secreted by the whooping cough agent Bordetella pertussis,
is one of the most complex soluble bacterial proteins. It is actively secreted through the B …

Pertussis, also known as whooping cough, is a respiratory disease caused by infection with
Bordetella pertussis, which releases several virulence factors, including the AB-type …

Pertussis toxin (PT), a secreted virulence factor of Bordetella pertussis, ADP ribosylates
mammalian Gi proteins and plays an important early role in respiratory tract infection by this …

The active subunit (S1) of pertussis toxin (PT), a major virulence factor of Bordetella
pertussis, ADP-ribosylates Gi proteins in the mammalian cell cytosol to inhibit GPCR …