Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity

D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …

Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity: a blind-verified study

MA Leone, O Raymkulova, P Naldi, P Lochner… - PLoS …, 2013 - journals.plos.org
Background Chronic Cerebrospinal Venous Insufficiency (CCSVI) has been associated with
multiple sclerosis (MS) with a risk ranging from as high as two-hundred-fold to a protective …

Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study

IW Rodger, D Dilar, J Dwyer, J Bienenstock, A Coret… - PLoS …, 2013 - journals.plos.org
Objective Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS.
Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study

S Bastianello, A Romani, G Viselner, EC Tibaldi… - BMC neurology, 2011 - Springer
Background Chronic cerebrospinal venous insufficiency (CCSVI) has recently been reported
to be associated with multiple sclerosis (MS). However, its actual prevalence, possible …

Clinical correlates of chronic cerebrospinal venous insufficiency in multiple sclerosis

B Weinstock-Guttman, M Ramanathan, K Marr… - BMC neurology, 2012 - Springer
Background Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition
characterized by anomalies of the primary veins outside the skull that has been reported to …

Progressive multiple sclerosis is not associated with chronic cerebrospinal venous insufficiency

C Baracchini, P Perini, F Causin, M Calabrese… - Neurology, 2011 - AAN Enterprises
Objective: Chronic cerebrospinal venous insufficiency (CCSVI) had been suggested to play
a major pathogenetic role in multiple sclerosis (MS), but recent data on early stages of MS …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon

R Lanzillo, M Mancini, R Liuzzi, O Di Donato… - BMC neurology, 2013 - Springer
Background This study aimed to investigate the prevalence and clinical relevance of chronic
cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy …

Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study

G Comi, MA Battaglia, A Bertolotto… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a
possible cause of multiple sclerosis (MS). Objectives: The CoSMo study evaluated the …

Multiple sclerosis and CCSVI: a population-based case control study

F Patti, A Nicoletti, C Leone, S Messina, E D'Amico… - 2012 - journals.plos.org
Background Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to
multiple sclerosis (MS). Objective To evaluate the possible association between CCSVI and …

Chronic cerebrospinal venous insufficiency is not more prevalent in patients with mild multiple sclerosis: a sonographer-blinded, case-control ultrasound study

B Chambers, J Chambers, H Cameron… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Objectives: We designed a prospective case-control study of patients with clinically isolated
syndrome (CIS) and Relapsing–Remitting Multiple Sclerosis (RRMS) with an Expanded …