Meta-analysis of the correlation between chronic cerebrospinal venous insufficiency and multiple sclerosis

BA Zwischenberger, MM Beasley… - Vascular and …, 2013 - journals.sagepub.com
Purpose: To determine whether a correlation exists between chronic cerebrospinal venous
insufficiency (CCSVI) and multiple sclerosis (MS). Materials and Methods: A meta-analysis …

Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS

R Zivadinov, K Marr, G Cutter, M Ramanathan… - Neurology, 2011 - AAN Enterprises
Background: Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in
patients with multiple sclerosis (MS). A subject is considered CCSVI positive if≥ 2 venous …

Chronic cerebrospinal venous insufficiency and multiple sclerosis: a comprehensive meta-analysis of case–control studies

G Tsivgoulis, TN Sergentanis, A Chan… - Therapeutic …, 2014 - journals.sagepub.com
Objectives: Chronic cerebrospinal venous insufficiency (CCSVI) has recently been
implicated in the pathogenesis of multiple sclerosis (MS). This comprehensive meta-analysis …

No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset

C Baracchini, P Perini, M Calabrese… - Annals of …, 2011 - Wiley Online Library
Objective An impaired cerebrospinal venous drainage, defined as chronic cerebrospinal
venous insufficiency (CCSVI), has been recently hypothesized to be the possible cause of …

Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis

P Zamboni, R Galeotti, E Menegatti… - Journal of Neurology …, 2009 - jnnp.bmj.com
Background: The extracranial venous outflow routes in clinically defined multiple sclerosis
(CDMS) have not previously been investigated. Methods: Sixty-five patients affected by …

Italian multicentre observational study of the prevalence of CCSVI in multiple sclerosis (CoSMo study): rationale, design, and methodology

G Comi, MA Battaglia, A Bertolotto, M Del Sette… - Neurological …, 2013 - Springer
Chronic cerebro-spinal venous insufficiency (CCSVI) has been proposed as a “congenital
malformation” implicated in the pathogenesis of multiple sclerosis (MS). However, numerous …

The hypothesis of pathophysiological correlation between chronic cerebrospinal venous insufficiency and multiple sclerosis: rationale of treatment

M Lugli, M Morelli, S Guerzoni, O Maleti - Phlebology, 2012 - journals.sagepub.com
Background: The possible role of the venous system in the pathogenesis of chronic
neurodegenerative diseases has been hypothesized for decades. Quite recently, the …

Chronic cerebrospinal venous insufficiency and venous stenoses in multiple sclerosis

M Blinkenberg, P Åkeson, H Sillesen… - Acta neurologica …, 2012 - Wiley Online Library
Objectives The traditional view that multiple sclerosis (MS) is an autoimmune disease has
recently been challenged by the claim that MS is caused by chronic cerebrospinal venous …

Using magnetic resonance imaging as a means to study chronic cerebral spinal venous insufficiency in multiple sclerosis patients

D Utriainen, W Feng, S Elias, Z Latif, D Hubbard… - Techniques in vascular …, 2012 - Elsevier
The goal of this work is to present a broad magnetic resonance imaging (MRI) protocol for
use in the study of chronic cerebrospinal venous insufficiency (CCSVI). The CCSVI MRI …

Chronic cerebrospinal venous insufficiency and multiple sclerosis

O Khan, M Filippi, MS Freedman, F Barkhof… - Annals of …, 2010 - Wiley Online Library
A chronic state of impaired venous drainage from the central nervous system, termed
chronic cerebrospinal venous insufficiency (CCSVI), is claimed to be a pathologic …