Objective To investigate the ability of anti–endothelial cell antibodies (AECA) to modulate
endothelial cell function. Methods The effects of purified IgG from 11 patients with systemic …

Purpose Although immunologic mechanisms have been postulated in the pathogenesis of
vasculitis, an autoimmune process directed against specific autologous vascular wall …

Antiendothelial cell antibodies (AECA), a heterogeneous group of antibodies quite distinct
from the ANCA family, have been detected in variety of diseases which share a varying …

Materials and methods Antinuclear antibodies (ANA) were detected by reacting sera with
mouse liver sections and fluoresceinconjugated antihuman IgG. Antisera to humanplasma …

OBJECTIVE: To determine if anti-endothelial cell antibodies (AECA) and plasma markers of
endothelial cell function are related to disease severity in systemic lupus erythematosus …

In primary systemic vasculitis anti endothelial cell autoantibodies (AECA) have been
described frequently. They represent a heterogeneous group of autoantibodies whose target …

Heating sera is used to inactivate complement but may affect the binding characteristics of
autoantibodies. We studied the effect of heating sera from patients with systemic vasculitides …

IgG autoantibodies that bind human endothelial cells (AECA) were detected by ELISA in 30
of 42 samples of sera from patients with scleroderma. Pretreatment of human umbilical vein …

Antiendothelial cell antibodies (AECA) have been detected by flow cytometry analysis in 23
out of 80 patients with connective tissue diseases. Ten out of 19 serum samples from …

A humoral response against vascular tissues was suggested more than twenty years ago by
Lind-qvist and Osterland (1971) and Tan and Pearson (1972). In the following years, little …