There is overwhelming evidence that oxidative stress and oxidative damage play a pivotal
role in the pathogenesis of chronic obstructive pulmonary disease (COPD)(1-3). The …

There is now considerable evidence for an increased oxidant burden in patients with chronic
obstructive pulmonary disease (COPD). Oxidative stress is a critical feature in the …

Chronic obstructive pulmonary disease (COPD) is a slowly progressive condition
characterised by airflow limitation, which is largely irreversible [1]. The main aetiological …

AM J RESPIR CRIT CARE MED 1999; 160: S58− S65. There is now increasing evidence
that an oxidant/antioxidant imbalance, in favor of oxidants, occurs in chronic obstructive …

There is a marked increase in oxidative stress in the lungs of patients with COPD, as
measured by increased exhaled 8-isoprostane, ethane, and hydrogen peroxide in the …

An imbalance between oxidants and antioxidants is considered to play a role in the
pathogenesis of chronic obstructive pulmonary disease (COPD). There is considerable …

Oxidative stress occurs when free radicals and other reactive species overwhelm the
availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and …

There is now considerable evidence for an increased oxidant burden in smokers,
particularly in those smokers who develop chronic obstructive pulmonary disease (COPD) …

Chronic inflammation and oxidative stress are important features in the pathogenesis of
COPD. The increased oxidative stress in patients with COPD is the result of an increased …

Chronic obstructive pulmonary disease (COPD) is characterised by the progressive
development of airflow limitation that is not fully reversible. The clinical syndrome of COPD …