Background Increasing evidence suggests adipocyte involvement in malignant breast tumor
invasive front or margin. The aim of this study was to evaluate the location of invasive breast …

The fat-gland interface in the breast is noteworthy in that major vessels and lymphatic
channels supplying the breast are located there; however, the relationship between breast …

Adipose tissue is a dynamic organ that provides endocrine, inflammatory and angiogenic
factors, which can assist breast carcinoma cells with invasion and metastasis. Previous …

Purpose To investigate the relationship between spiculated masses at mammography and
marginal adipose tissue invasion at histologic examination. Materials and Methods The …

The process of tumor formation and progression is a result of the complex interaction
between malignant epithelial cells and the various cell populations in the tumor …

Background Interactions between adipocyte and breast cancer (BC) cells have yet to be fully
elucidated. Here we investigated the prognostic impact of marginal adipose tissue invasion …

Purpose Clinical, imaging and outcome observations indicate that diffusely infiltrating breast
cancer, presenting as a large region of architectural distortion on the mammogram and …

The tissue stroma plays a major role in tumors' natural history. Most programs for tumor
progression are not activated as cell-autonomous processes but under the conditions of …

Background and purposes The aim of this study was to develop morphological analytic
methods to analyze the tumor-fat interface and in different peritumoral shells away from the …

Objective Despite the lack of reliable methods with which to measure breast density from 2D
mammograms, numerous studies have demonstrated a positive association between breast …