Advances in understanding the molecular mechanisms of tumor progression have achieved
impressive progress in the treatment of cancer and so-called immune checkpoint inhibitors …

The development of so-called immune checkpoint inhibitors (ICIs), which target specific
molecular processes of tumour growth, has had a transformative effect on cancer treatment …

The rising incidence and persistent thrombosis in multiple cancers including those that are
immunosuppressive highlight the need for understanding the tumor coagulome system and …

Hypercoagulation is a common feature of several tumors to the extent that individuals with
coagulation defects often present with occult visceral cancers. Recent evidence has shown …

Pathological activation of the coagulation system occurs with virtually all forms of cancer,
particularly epithelial malignancies. Accordingly, thrombosis is one of the most common …

Several studies have suggested a role for blood coagulation proteins in tumour progression.
Herein, we discuss (1) the activation of the blood clotting cascade in the tumour …

The last half century of cancer research has seen an explosion in our understanding of the
complex interplay between cancer cells and host-derived factors critical for cancer …

Pathogenesis of the prothrombotic state of cancer patients is due, at least in part, to the
ability of cancer cells to activate the coagulation system. Several complex and not fully …

Cancer-associated thrombosis remains a significant complication in the clinical
management of cancer and interactions of the hemostatic system with cancer biology …

The clinical link between cancer and thrombosis has been recognized by Armand
Trousseau in 1865. It has now become clear that clotting activation in malignancy not only …