Considerations to maximize fat mass gain in a mouse model of diet-induced weight gain

KC Carpenter, K Strohacker… - Laboratory animals, 2013 - journals.sagepub.com
Mouse experimental models of diet-induced weight gain are commonly used as analogs to
human obesity; however, a wide variety of feeding methods have been used and the most …

Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of post-natal malnutrition

LP Kozak, RA Koza, R Anunciado-Koza, T Mendoza… - PLoS …, 2012 - journals.plos.org
Interscapular brown adipose tissue (iBAT) is formed during fetal development and stable for
the life span of the mouse. In addition, brown adipocytes also appear in white fat depots …

Fat and carbohydrate content in the diet induces drastic changes in gene expression in young Göttingen minipigs

CM Junker Mentzel, T Figueiredo-Cardoso, AMJ Lex… - 2017 - digital.csic.es
In human health, there is interest in developing specific diets to reduce body weight. These
studies are mainly focused on phenotypic changes induced in blood measurements, ie …

Molecular correlates of fat mass expansion in C57BL/6J mice after short‐term exposure to dietary fat

RP Anunciado‐Koza, J Manuel… - Annals of the New York …, 2016 - Wiley Online Library
Heterogeneity of obesity within a population of inbred mice fed an obesogenic high‐fat diet
(HFD) is associated with changes of gene expression in white adipose tissue (WAT). One …

The Role of Fasting Interventions on Skeletal Muscle in High Fat Diet Fed Mice

M Puppa, A Persinger, K Brown, R Wible… - The FASEB …, 2019 - Wiley Online Library
Obesity is a growing epidemic worldwide leading to growing rates of chronic disease and
diabetes. A diet rich in omega‐6 fatty acids and refined sugars, known as the “Western diet,” …

Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains

JM Cheverud, LS Pletscher… - Physiological …, 1999 - journals.physiology.org
Cheverud, James M., L. Susan Pletscher, Ty T. Vaughn, and Bess Marshall. Differential
response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains. Physiol …

The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation

S Cirera, E Taşöz, M Juul Jacobsen… - Nutrition & …, 2020 - nature.com
Background Model animals are valuable resources for dissecting basic aspects of the
regulation of obesity and metabolism. The translatability of results relies on understanding …

Obesity development and signs of metabolic abnormalities in young Göttingen minipigs consuming energy dense diets varying in carbohydrate quality

MV Curtasu, M Skou Hedemann, H Nygaard Lærke… - Nutrients, 2021 - mdpi.com
Consumption of fructose has been associated with a higher risk of developing obesity and
metabolic syndrome (MetS). The aim of this study was to examine the long-term effects of …

Life Long High Fat Diet Causes Hepatic Lipid Accumulation by Programming Lipid Synthesis Genes in Liver of Male Rat

PM Jung, D Zhou, L Moody, A Kriska… - The FASEB …, 2016 - Wiley Online Library
Life long high fat (HF) diet has been shown to cause more hepatic lipid accumulation in
offspring as compared to a post‐weaning HF diet. However, it is still unclear what the …

Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice

NJW De Wit, MV Boekschoten, EM Bachmair… - PLoS …, 2011 - journals.plos.org
Excessive intake of dietary fat is known to be a contributing factor in the development of
obesity. In this study, we determined the dose-dependent effects of dietary fat on the …