Dissolving polymer microneedles for transdermal delivery of insulin
N Zhang, X Zhou, L Liu, L Zhao, H Xie… - Frontiers in …, 2021 - frontiersin.org
It's of great significance to develop insulin-loaded dissolving microneedles (MNs) which are
fabricated with various methods and materials for transdermal delivery of insulin to …
fabricated with various methods and materials for transdermal delivery of insulin to …
Formulation of two‐layer dissolving polymeric microneedle patches for insulin transdermal delivery in diabetic mice
Dissolving microneedles (MNs) display high efficiency in delivering poorly permeable drugs
and vaccines. Here, two‐layer dissolving polymeric MN patches composed of gelatin and …
and vaccines. Here, two‐layer dissolving polymeric MN patches composed of gelatin and …
In vitro and in vivo assessment of polymer microneedles for controlled transdermal drug delivery
Microneedles (MNs) system for transdermal drug delivery has the potential to improve
therapeutic efficacy, proving an approach that is more convenient and acceptable than …
therapeutic efficacy, proving an approach that is more convenient and acceptable than …
Implantable powder-carrying microneedles for transdermal delivery of high-dose insulin with enhanced activity
Recently, numerous transdermal drug delivery systems have been developed for safe and
efficient delivery of biopharmaceuticals. Dissolving microneedles (DMNs) are one such drug …
efficient delivery of biopharmaceuticals. Dissolving microneedles (DMNs) are one such drug …
Dissolving microneedle patches for transdermal insulin delivery in diabetic mice: potential for clinical applications
CH Chen, VBH Shyu, CT Chen - Materials, 2018 - mdpi.com
In this study, dissolving polymeric microneedle (MN) patches composed of gelatin and
sodium carboxymethyl cellulose (CMC) were used to localize insulin. Their in vitro skin …
sodium carboxymethyl cellulose (CMC) were used to localize insulin. Their in vitro skin …
Fabrication of composite microneedles integrated with insulin-loaded CaCO3 microparticles and PVP for transdermal delivery in diabetic rats
Dissolving microneedles (MNs) display high efficiency, safety and painless in transdermal
delivery for poorly permeable drugs. Here, a dissolving composite MNs prepared from …
delivery for poorly permeable drugs. Here, a dissolving composite MNs prepared from …
Dissolving microneedle rollers for rapid transdermal drug delivery
Dissolving microneedle patch (DMNP) is a minimally invasive and painless self-
administration device. However, due to skin deformation, it is difficult to apply it on the large …
administration device. However, due to skin deformation, it is difficult to apply it on the large …
Dissolving polymer microneedle patches for rapid and efficient transdermal delivery of insulin to diabetic rats
MH Ling, MC Chen - Acta biomaterialia, 2013 - Elsevier
This study presents a dissolving microneedle patch, composed of starch and gelatin, for the
rapid and efficient transdermal delivery of insulin. The microneedles completely dissolve …
rapid and efficient transdermal delivery of insulin. The microneedles completely dissolve …
Fabrication of novel-shaped microneedles to overcome the disadvantages of solid microneedles for the transdermal delivery of insulin
Y Mizuno, K Takasawa, T Hanada, K Nakamura… - Biomedical …, 2021 - Springer
In this study, we fabricated two different microneedles (MNs)—semi-hollow and bird-bill—to
overcome the limitations of solid and coated MNs, respectively. The two MN arrays were …
overcome the limitations of solid and coated MNs, respectively. The two MN arrays were …
Practicality of non-invasive glucagon-loaded dissolving microneedle for life-saving treatment of severe hypoglycemia in a diabetic rat model
X Wang, Y Ma, X Qi, X Ruan, D Cao, F Zhao - International Journal of …, 2023 - Elsevier
The development of dissolving microneedles (DMNs) has brought light to the transdermal
delivery of biomolecules that are released into the skin through the rapid dissolution of the …
delivery of biomolecules that are released into the skin through the rapid dissolution of the …
相关搜索
- diabetic rats transdermal delivery
- polymer microneedles transdermal delivery
- microneedle patches insulin delivery
- diabetic mice insulin delivery
- microneedle arrays drug delivery
- clinical applications insulin delivery
- caco3 microparticles transdermal delivery
- enhanced activity transdermal delivery
- composite microneedles transdermal delivery
- solid microneedles transdermal delivery
- polymer microneedles drug delivery
- microneedle rollers drug delivery