Objectives To explain methods for data synthesis of evidence from diagnostic test accuracy
(DTA) studies, and to illustrate different types of analyses that may be performed in a DTA …

Meta-analysis of diagnostic accuracy studies requires the use of more advanced methods
than metaanalysis of intervention studies. This is due to the fact that test performance is …

Background There has been an increase in the number of systematic reviews of diagnostic
tests, which has resulted in the introduction of two checklists: statement for reporting of …

Background Diagnostic evidence of the accuracy of a test for identifying a target condition of
interest can be estimated using systematic approaches following standardized …

Background The last decade has seen a number of methodological developments in meta-
analysis of diagnostic test studies. However, it is unclear whether such developments have …

Understanding diagnostic test accuracy (DTA) data, especially meta‐analysis of this
information, can be challenging for researchers and clinicians. The use of plots of receiver …

The statistical aspects of a systematic review of test accuracy are more challenging than
those for reviews of interventions. It is therefore recommended that review teams include an …

Abstract The Cochrane Collaboration says that the Cochrane handbook for diagnostic test
accuracy reviews (DTAR) is currently in development as per the Cochrane Collaboration …

The statistical aspects of a systematic review of diagnostic test accuracy are more
challenging than for reviews of interventions, and it is recommended that review teams …

Background Recommended statistical methods for meta-analysis of diagnostic test accuracy
studies require relatively complex bivariate statistical models which can be a barrier for non …