Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

First steps towards a vaccine against Acinetobacter baumannii

M Garcia-Quintanilla, MR Pulido… - Current …, 2013 - ingentaconnect.com
Acinetobacter baumannii has become an important cause of human infections, most notably
in the hospital setting. In addition, the global dissemination of multidrug resistant strains has …

Subunit vaccines for Acinetobacter baumannii

N Yang, X Jin, C Zhu, F Gao, Z Weng, X Du… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen
in hospitals. A. baumannii infection has become a challenging problem in clinical practice …

Recent Advances in the Pursuit of an Effective Acinetobacter baumannii Vaccine

PS Gellings, AA Wilkins, LA Morici - Pathogens, 2020 - mdpi.com
Acinetobacter baumannii has been a major cause of nosocomial infections for decades. The
absence of an available vaccine coupled with emerging multidrug resistance has prevented …

Current advances and challenges in the development of Acinetobacter vaccines

W Chen - Human vaccines & immunotherapeutics, 2015 - Taylor & Francis
Acinetobacter baumannii is a major cause of healthcare-associated infections worldwide
with high morbidity and mortality. The clinical treatment of A. baumannii infections has …

Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It

C Ma, S McClean - Vaccines, 2021 - mdpi.com
Acinetobacter baumannii is a leading cause of nosocomial infections that severely threaten
public health. The formidable adaptability and resistance of this opportunistic pathogen have …

Immunization with a 22-kDa outer membrane protein elicits protective immunity to multidrug-resistant Acinetobacter baumannii

W Huang, Y Yao, S Wang, Y Xia, X Yang, Q Long… - Scientific reports, 2016 - nature.com
A. baumannii infections are becoming more and more serious health issues with rapid
emerging of multidrug and extremely drug resistant strains, and therefore, there is an urgent …

Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development

NA Mat Rahim, HY Lee, U Strych… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT In 2017, the World Health Organization (WHO) named A. baumannii as one of
the three antibiotic-resistant bacterial species on its list of global priority pathogens in dire …

[HTML][HTML] Vaccines for Acinetobacter baumannii: thinking “out of the box”

F Perez, RA Bonomo - Vaccine, 2014 - ncbi.nlm.nih.gov
We are indeed fortunate that modern medicine continues to offer advancements that
promise better and longer lives. Delivering on that promise depends on our ability to …

Combination of BauA and OmpA elicit immunoprotection against Acinetobacter baumannii in a murine sepsis model

M Tamehri, I Rasooli, M Pishgahi, A Jahangiri… - Microbial …, 2022 - Elsevier
Aims Acinetobacter baumannii causes severe nosocomial infections and is a difficult-to-treat
pathogen due to the development of multidrug-resistant (MDR) strains. Vaccines and …