Cognitive Deficits in Parkinson's Disease Are Associated with Neuronal Dysfunction and Not White Matter Lesions

N Schröter, T Bormann, M Rijntjes… - Movement Disorders …, 2023 - Wiley Online Library
Background Cognitive deficits considerably contribute to the patient's burden in Parkinson's
disease (PD). While cognitive decline is linked to neuronal dysfunction, the additional role of …

White matter hyperintensities related to Parkinson's disease executive function

P Linortner, C McDaniel, M Shahid… - Movement disorders …, 2020 - Wiley Online Library
Abstract Background People with Parkinson's disease (PD) can develop multidomain
cognitive impairments; however, it is unclear whether different pathologies underlie domain …

Cognitive impairment in nondemented Parkinson's disease

P Barone, D Aarsland, D Burn, M Emre… - Movement …, 2011 - Wiley Online Library
A substantial percentage of patients with newly diagnosed Parkinson's disease without
dementia are reported to be affected by cognitive impairment (CI). In practice, however, CI is …

Longitudinal white matter damage evolution in Parkinson's disease

PG Scamarcia, F Agosta, EG Spinelli… - Movement …, 2022 - Wiley Online Library
ABSTRACT Background White matter hyperintensities (WMHs) have a role in cognitive
impairment in normal brain aging, while the effect on Parkinson's disease (PD) progression …

White Matter Microstructural Underpinnings of Mild Behavioral Impairment in Parkinson's Disease

O Monchi, GD Pinilla‐Monsalve, H Almgren… - Movement …, 2024 - Wiley Online Library
Abstract Background Patients with Parkinson's disease (PD) experience changes in
behavior, personality, and cognition that can manifest even in the initial stages of the …

Subjective cognitive complaint in Parkinson's disease patients with normal cognition: canary in the coal mine?

R Purri, L Brennan, J Rick, SX Xie, BL Deck… - Movement …, 2020 - Wiley Online Library
Objective The objective of this study was to determine the frequency and impact of
subjective cognitive complaint (SCC) in Parkinson's disease (PD) patients with normal …

Cognitive impairment in Parkinson's disease: tools for diagnosis and assessment

J Kulisevsky, J Pagonabarraga - Movement disorders, 2009 - Wiley Online Library
Cognitive impairment (CI) and dementia are frequent and debilitating features associated
with Parkinson's disease (PD). Formal neuropsychological examination is required to …

The pattern of cortical atrophy in patients with Parkinson's disease according to cognitive status

SK Song, JE Lee, HJ Park, YH Sohn… - Movement …, 2011 - Wiley Online Library
Background: Cognitive dysfunction is common in Parkinson's disease (PD), and along with
PD with dementia (PDD), the concept of mild cognitive impairment in PD (PD‐MCI) has been …

APOE, thought disorder, and SPARE‐AD predict cognitive decline in established Parkinson's disease

TF Tropea, SX Xie, J Rick, LM Chahine… - Movement …, 2018 - Wiley Online Library
Background People with PD are at high risk of developing cognitive impairment and
dementia. Cross‐sectional studies have identified candidate biomarkers associated with …

Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease

D Weintraub, T Simuni, C Caspell‐Garcia… - Movement …, 2015 - Wiley Online Library
This study was undertaken to determine the prevalence and correlates of cognitive
impairment (CI) and neuropsychiatric symptoms (NPS) in early, untreated patients with …