Current epidemiologic and genetic data suggest the hypothetical paradigm that prostate
cancer occurs in three forms: sporadic, familial, and hereditary (Figure 1). Sporadic cases …

Although all men are at increased risk for prostate cancer developing with increasing age, a
family history of prostate cancer in a first-degree relative multiplies that risk approximately …

BACKGROUND Although all men age> 50 years are at an increased risk for the
development of prostate carcinoma, 2 major factors increase this risk: family history and …

Prostate cancer has been known to run in families for about 40 years and epidemiological
studies have demonstrated an increased risk to close relatives of cases. This risk rises …

Purpose: We evaluated the importance of positive family history, age at diagnosis and
history of vasectomy in predicting the risk for prostate cancer in the brothers of prostate …

Prostate cancer is a significant public health problem. There are about 14000 cases per year
in England and Wales, and 10000 deaths [J]. In the USA, it is the most common malignancy …

BACKGROUND Although prostate carcinoma is not widely recognized as a familial cancer,
familial aggregation of this disease has been shown in some retrospective case–control …

Prostate cancer is the most common cancer in men and the second highest cause of cancer-
related mortality in the UK A genetic component in predisposition to prostate cancer has …

The three most important recognized risks for prostate cancer (PCa) are increasing age,
ancestry, and family history of the disease. The clustering of PCa within families can be …

OBJECTIVE: To review current literature on the hereditary aspects of prostate cancer and to
evaluate the importance of family history in history taking and screening for prostate cancer …