[HTML][HTML] Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients

B Buijsers, C Yanginlar, ML Maciej-Hulme… - …, 2020 - thelancet.com
Abstract Coronavirus disease-2019 (COVID-19) is associated with severe inflammation in
mainly the lung, and kidney. Reports suggest a beneficial effect of the use of heparin/low …

[HTML][HTML] Use of enoxaparin to counteract COVID-19 infection and reduce thromboembolic venous complications: a review of the current evidence

F Drago, L Gozzo, L Li, A Stella, B Cosmi - Frontiers in pharmacology, 2020 - frontiersin.org
The impact of the COVID-19 pandemic has been dramatic worldwide, with China, Italy, and
now US at its epicenter. Researchers and clinicians are studying and testing different …

Heparin as a therapy for COVID-19: current evidence and future possibilities

JA Hippensteel, WB LaRiviere… - … of Physiology-Lung …, 2020 - journals.physiology.org
Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every …

[HTML][HTML] The potential role of heparin in patients with COVID-19: beyond the anticoagulant effect. A review

L Gozzo, P Viale, L Longo, DC Vitale… - Frontiers in …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is responsible of
variable clinical manifestations, ranging from no symptoms to severe pneumonia with acute …

Comprehensive landscape of heparin therapy for COVID-19

C Shi, W Tingting, JP Li, MA Sullivan, C Wang… - Carbohydrate …, 2021 - Elsevier
The pandemic coronavirus disease 2019 (COVID-19), caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading globally …

[HTML][HTML] Preliminary experience with low molecular weight heparin strategy in COVID-19 patients

P Paolisso, L Bergamaschi, EC D'Angelo… - Frontiers in …, 2020 - frontiersin.org
Background Heparin administration in COVID-19 patients is recommended by expert
consensus, although evidence about dosage, duration and efficacy are limited. We aim to …

[HTML][HTML] Inhaled and systemic heparin as a repurposed direct antiviral drug for prevention and treatment of COVID-19

C Conzelmann, JA Müller, L Perkhofer, KMJ Sparrer… - Clinical Medicine, 2020 - Elsevier
Here, we advocate a highly favourable opportunity for the treatment of COVID-19 disease by
repurposing a long-serving medical agent with an excellent history of clinical use, namely …

[HTML][HTML] Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo… - Thrombosis and …, 2021 - thieme-connect.com
Introduction A hypercoagulable condition was described in patients with coronavirus
disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing …

Using heparin molecules to manage COVID‐2019

J Liu, J Li, K Arnold, R Pawlinski… - Research and practice …, 2020 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic is becoming one of the
largest global public health crises in modern history. The race for an effective drug to prevent …

The potential of low molecular weight heparin to mitigate cytokine storm in severe COVID‐19 patients: a retrospective cohort study

C Shi, C Wang, H Wang, C Yang, F Cai… - Clinical and …, 2020 - Wiley Online Library
On March 11, 2020, the World Health Organization declared its assessment of coronavirus
disease 2019 (COVID‐19) as a global pandemic. However, specific anti‐severe acute …