[HTML][HTML] Genome-wide analysis of DNA methylation associated with HIV infection based on a pair of monozygotic twins
Y Zhang, SK Li, SKW Tsui - Genomics Data, 2015 - Elsevier
Alteration of DNA methylation in mammalian cells could be elicited by many factors,
including viral infections [1]. HIV has shown the ability to interact with host cellular factors to …
including viral infections [1]. HIV has shown the ability to interact with host cellular factors to …
Whole genome methylation array reveals the down-regulation of IGFBP6 and SATB2 by HIV-1
Nowadays, the knowledge in DNA methylation-mediated gene regulation has shed light on
the understanding of virus-host interplay in the context of genome alteration. It has also been …
the understanding of virus-host interplay in the context of genome alteration. It has also been …
HIV infection alters the human epigenetic landscape
Many complex diseases or traits are the results of both genetic and environmental factors.
The environmental factors affect the human body by modifying its epigenetics, which …
The environmental factors affect the human body by modifying its epigenetics, which …
Deciphering DNA methylation in HIV infection
T Arumugam, U Ramphal, T Adimulam… - Frontiers in …, 2021 - frontiersin.org
With approximately 38 million people living with HIV/AIDS globally, and a further 1.5 million
new global infections per year, it is imperative that we advance our understanding of all …
new global infections per year, it is imperative that we advance our understanding of all …
Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals
Background The HIV-1 proviral genome harbors multiple CpG islands (CpGIs), both in the
promoter and intragenic regions. DNA methylation in the promoter region has been shown …
promoter and intragenic regions. DNA methylation in the promoter region has been shown …
Epigenome-wide association scan identifies methylation sites associated with HIV infection
Aim: To investigate the role of epigenetics in HIV pathophysiology. Materials&methods: We
conducted an epigenome-wide association scan on HIV infection status among people who …
conducted an epigenome-wide association scan on HIV infection status among people who …
Genome-wide characterization of host transcriptional and epigenetic alterations during HIV infection of T lymphocytes
X Zeng, JCC Tsui, M Shi, J Peng, CY Cao… - Frontiers in …, 2020 - frontiersin.org
Background and methods: Host genomic alterations are closely related to dysfunction of
CD4+ T lymphocytes in the HIV–host interplay. However, the roles of aberrant DNA …
CD4+ T lymphocytes in the HIV–host interplay. However, the roles of aberrant DNA …
Effect of HIV infection and antiretroviral therapy initiation on genome-wide DNA methylation patterns
A Esteban-Cantos, J Rodríguez-Centeno, JC Silla… - …, 2023 - thelancet.com
Background Previous epigenome-wide association studies have shown that HIV infection
can disrupt the host DNA methylation landscape. However, it remains unclear how …
can disrupt the host DNA methylation landscape. However, it remains unclear how …
Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals
Epigenetic control of human immunodeficiency virus-1 (HIV-1) genes is critical for viral
integration and latency. However, epigenetic changes in the HIV-1-infected host genome …
integration and latency. However, epigenetic changes in the HIV-1-infected host genome …
Integrative analysis of methylome and transcriptome in human blood identifies extensive sex-and immune cell-specific differentially methylated regions
S Mamrut, N Avidan, E Staun-Ram, E Ginzburg… - Epigenetics, 2015 - Taylor & Francis
The relationship between DNA methylation and gene expression is complex and elusive. To
further elucidate these relations, we performed an integrative analysis of the methylome and …
further elucidate these relations, we performed an integrative analysis of the methylome and …
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