Inhaled corticosteroids: potency, dose equivalence and therapeutic index

PT Daley‐Yates - British journal of clinical pharmacology, 2015 - Wiley Online Library
Glucocorticosteroids are a group of structurally related molecules that includes natural
hormones and synthetic drugs with a wide range of anti‐inflammatory potencies. For …

Inhaled corticosteroid doses in asthma: an evidence‐based approach

H Powell, PG Gibson - Medical journal of Australia, 2003 - Wiley Online Library
Objective: To define the evidence for doses of inhaled corticosteroids in asthma and
describe this in clinically meaningful, evidence‐based terms. Data source: Cochrane …

Inhaled corticosteroids in children: effects on bone mineral density and growth

AL Fuhlbrigge, HW Kelly - The Lancet Respiratory Medicine, 2014 - thelancet.com
Potent, topically active corticosteroids with minimum systemic activity have fewer adverse
effects than do systemic corticosteroids, and can control both asthma and allergic rhinitis …

Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma: collaboration of American College of Chest Physicians …

FT Leone, JE Fish, SJ Szefler, SL West - Chest, 2003 - Elsevier
Introduction The available clinical guidelines have been successful in improving awareness
of the inflammatory nature of asthma and have promoted the use of inhaled corticosteroids …

Safety of inhaled corticosteroids in the treatment of persistent asthma.

SP Peters - Journal of the National Medical Association, 2006 - ncbi.nlm.nih.gov
OBJECTIVE: Inhaled corticosteroids (ICSs) are the most effective medications available for
patients with persistent asthma of all severities and currently are recommended as the …

Once-daily inhaled corticosteroids in mild to moderate asthma: improving acceptance of treatment

LM Campbell - Drugs, 1999 - Springer
Despite the established efficacy of inhaled corticosteroids in improving lung function in
asthma, there has not been a corresponding improvement in morbidity and mortality …

Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma

H Derendorf, R Nave, A Drollmann… - European …, 2006 - Eur Respiratory Soc
The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have
shaped the efficacy and safety of these agents in the treatment of asthma. Important …

Effects of inhaled corticosteroids on the consequences of asthma

HA Boushey - Journal of allergy and clinical immunology, 1998 - Elsevier
Asthma is a chronic inflammatory disease of the airways involving a characteristic pattern of
airway infiltration with lymphocytes, eosinophils, and mast cells, subepithelial deposition of …

Inhaled and nasal corticosteroids: factors affecting the risks of systemic adverse effects

A Cave, P Arlett, E Lee - Pharmacology & therapeutics, 1999 - Elsevier
There has been increasing concern in the medical literature about the safety of inhaled and
nasal corticosteroids, since many patients, both adults and children, are increasingly …

Inhaled corticosteroids in COPD: the case against

S Suissa, PJ Barnes - European Respiratory Journal, 2009 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD), a disease that encompasses emphysema,
chronic obstructive bronchitis and small airway obstruction and that is characterised by …