Neuroinflammation in Parkinson's disease: role in neurodegeneration and tissue repair

S Vivekanantham, S Shah, R Dewji… - International Journal …, 2015 - Taylor & Francis
Neuroinflammation in Parkinson's disease [PD] is a process that occurs alongside the loss of
dopaminergic neurons, and is associated with alterations to many cell types, most notably …

Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention

MG Tansey, MK McCoy, TC Frank-Cannon - Experimental neurology, 2007 - Elsevier
Most acute and chronic neurodegenerative conditions are accompanied by
neuroinflammation; yet the exact nature of the inflammatory processes and whether they …

Inflammation in Parkinson's disease: mechanisms and therapeutic implications

M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …

Neuroinflammation in Parkinson's disease

JK Lee, T Tran, MG Tansey - Journal of Neuroimmune Pharmacology, 2009 - Springer
During the last two decades, a wealth of animal and human studies has implicated
inflammation-derived oxidative stress and cytokine-dependent neurotoxicity in the …

Parkinson's disease and enhanced inflammatory response

I Stojkovska, BM Wagner… - … biology and medicine, 2015 - journals.sagepub.com
Parkinson's disease (PD) is the first and second most prevalent motor and
neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of …

[PDF][PDF] Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy

MG Tansey, TC Frank-Cannon, MK McCoy, JK Lee… - Front Biosci, 2008 - researchgate.net
Overview 3. Clinical and epidemiological evidence for inflammation in Parkinson's Disease
3.1. Cell types involved in neuroinflammation 3.2. Inflammatory mediators in …

The role of neuroinflammation on the pathogenesis of Parkinson's disease

YC Chung, HW Ko, EG Bok, ES Park, SH Huh… - BMB …, 2010 - koreascience.kr
Parkinson's Disease (PD) is a common neurodegenerative disease characterized by the
progressive degeneration of nigrostriatal dopaminergic (DA) neurons. Although the …

The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: focus on astrocytes

R Niranjan - Molecular neurobiology, 2014 - Springer
Neuroinflammation plays a key role in the pathogenesis of Parkinson's disease (PD).
Epidemiologic, animal, human, and therapeutic studies support the role of oxidative stress …

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy

L Qian, PM Flood, JS Hong - Journal of neural transmission, 2010 - Springer
Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …