Tumor‐derived extracellular vesicles as a novel source of protein biomarkers for cancer diagnosis and monitoring

O Ruhen, K Meehan - Proteomics, 2019 - Wiley Online Library
Abstract “Liquid biopsies” have received attention as a complementary tool for traditional
tissue biopsies that may enhance the spectrum of analysis for tumor‐derived factors. One …

[HTML][HTML] Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

Extracellular vesicles and their potential use in monitoring cancer progression and therapy: the contribution of proteomics

MC Cufaro, D Pieragostino, P Lanuti… - Journal of …, 2019 - Wiley Online Library
Extracellular Vesicles (EVs) are small membrane‐enclosed particles released by cells and
able to vehiculate information between them. The term EVs categorizes many and different …

[HTML][HTML] Mass spectrometry-based proteome profiling of extracellular vesicles and their roles in cancer biology

R Bandu, JW Oh, KP Kim - Experimental & molecular medicine, 2019 - nature.com
Over the past three decades, extracellular vesicles (EVs) have arisen as important mediators
of intercellular communication that are involved in the transmission of biological signals …

Proteomic analysis of extracellular vesicles for cancer diagnostics

AYT Wu, K Ueda, CPK Lai - Proteomics, 2019 - Wiley Online Library
Extracellular vesicles (EVs) including exosomes and microvesicles are lipid bilayer‐
encapsulated nanoparticles released by cells, ranging from 40 nm to several microns in …

[HTML][HTML] Implications and pitfalls for cancer diagnostics exploiting extracellular vesicles

A Špilak, A Brachner, U Kegler, W Neuhaus… - Advanced drug delivery …, 2021 - Elsevier
Early detection of cancer in order to facilitate timely therapeutic interventions is an unsolved
problem in today's clinical diagnostics. Tumors are detected so far mostly after pathological …

Extracellular vesicles, the cornerstone of next-generation cancer diagnosis?

J Weng, X Xiang, L Ding, ALA Wong, Q Zeng… - Seminars in cancer …, 2021 - Elsevier
Cancer has risen up to be a major cause of mortality worldwide over the past decades.
Despite advancements in cancer screening and diagnostics, a significant number of cancers …

[PDF][PDF] Extracellular vesicles as a promising biomarker resource in liquid biopsy for cancer

T Tamura, Y Yoshioka, S Sakamoto, T Ichikawa… - Extracell. Vesicles Circ …, 2021 - f.oaes.cc
Liquid biopsy is a minimally invasive biopsy method that uses molecules in body fluids as
biomarkers, and it has attracted attention as a new cancer therapy tool. Liquid biopsy has …

Extracellular vesicle isolation, purification and evaluation in cancer diagnosis

K Mortezaee, J Majidpoor, F Fathi - Expert reviews in molecular …, 2022 - cambridge.org
Strategies for non-invasive biomarker discovery in early detection of cancer are an urgent
need. Extracellular vesicles (EVs) have generated increasing attention from the scientific …

Extracellular vesicles as cancer liquid biopsies: From discovery, validation, to clinical application

Z Zhao, J Fan, YMS Hsu, CJ Lyon, B Ning, TY Hu - Lab on a Chip, 2019 - pubs.rsc.org
Substantial research has been devoted to elucidate the roles that extracellular vesicles
(EVs) play in the regulation of both normal and pathological processes, and multiple studies …