Atrial fibrillation progression and the importance of early treatment for improving clinical outcomes

MA Gunawardene, S Willems - EP Europace, 2022 - academic.oup.com
Over time, atrial fibrillation (AF) naturally progresses from initially paroxysmal to
persistent/permanent AF caused by structural and electrical remodelling with a complex …

Early management of atrial fibrillation to prevent cardiovascular complications

S Nattel, E Guasch, I Savelieva, FG Cosio… - European heart …, 2014 - academic.oup.com
Atrial fibrillation (AF) is generally considered a progressive disease, typically evolving from
paroxysmal through persistent to 'permanent'forms, a process attributed to electrical and …

Can we improve outcomes in AF patients by early therapy?

P Kirchhof - BMC medicine, 2009 - Springer
Atrial fibrillation affects at least 1% of the population and causes marked society-wide
morbidity and mortality. Current management of atrial fibrillation including antithrombotic …

Rationale and current perspective for early rhythm control therapy in atrial fibrillation

IC Van Gelder, LM Haegeli, A Brandes… - Europace, 2011 - academic.oup.com
Atrial fibrillation (AF) is the most common sustained arrhythmia and an important source for
mortality and morbidity on a population level. Despite the clear association between AF and …

Avoiding permanent atrial fibrillation: treatment approaches to prevent disease progression

A Shukla, AB Curtis - Vascular health and risk management, 2013 - Taylor & Francis
Atrial fibrillation (AF) is the most common sustained arrhythmia and a major global public
health problem due to its associated morbidity, including stroke and heart failure, diminished …

A proposal for new clinical concepts in the management of atrial fibrillation

AJ Camm, SM Al-Khatib, H Calkins, JL Halperin… - American heart …, 2012 - Elsevier
Atrial fibrillation (AF) represents a growing public health burden. It is a complex condition,
involving a number of etiologic factors and arrhythmia mechanisms associated with atrial …

Delayed rhythm control of atrial fibrillation may be a cause of failure to prevent recurrences: reasons for change to active antiarrhythmic treatment at the time of the first …

FG Cosio, E Aliot, GL Botto, H Heidbüchel, CJ Geller… - Europace, 2008 - academic.oup.com
Atrial fibrillation (AF) is associated with impaired functional capacity and quality of life and
significant morbidity and mortality. The current management approach fails to maintain …

The Increasing Role of Rhythm Control in Patients With Atrial Fibrillation: JACC State-of-the-Art Review

AJ Camm, GV Naccarelli, S Mittal, HJGM Crijns… - Journal of the American …, 2022 - jacc.org
The considerable mortality and morbidity associated with atrial fibrillation (AF) pose a
substantial burden on patients and health care services. Although the management of AF …

Early and comprehensive management of atrial fibrillation: executive summary of the proceedings from the 2nd AFNET-EHRA consensus conference 'research …

P Kirchhof, J Bax, C Blomstrom-Lundquist… - European heart …, 2009 - academic.oup.com
Atrial fibrillation (AF) causes important mortality and morbidity on a population-level. So far,
we do not have the means to prevent AF or AF-related complications adequately. Therefore …

The progressive nature of atrial fibrillation: a rationale for early restoration and maintenance of sinus rhythm

IC Van Gelder, MEW Hemels - Europace, 2006 - academic.oup.com
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting young as
well as elderly patients and presenting a major therapeutic challenge for clinical …