Metabolic profiling regarding pathogenesis of idiopathic pulmonary fibrosis

YP Kang, SB Lee, J Lee, HM Kim… - Journal of proteome …, 2016 - ACS Publications
Idiopathic pulmonary fibrosis (IPF) is a progressive, eventually fatal disease characterized
by fibrosis of the lung parenchyma and loss of lung function. IPF is believed to be caused by …

Metabolic heterogeneity of idiopathic pulmonary fibrosis: a metabolomic study

YD Zhao, L Yin, S Archer, C Lu… - BMJ open …, 2017 - bmjopenrespres.bmj.com
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown
cause characterised by progressive fibrotic formation in lung tissue. We hypothesise that …

Quantitative proteomic characterization of lung tissue in idiopathic pulmonary fibrosis

Y Tian, H Li, Y Gao, C Liu, T Qiu, H Wu, M Cao… - Clinical proteomics, 2019 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive, eventually fatal disease.
IPF is characterized by excessive accumulation of the extracellular matrix (ECM) in the …

Serum proteomics identifies biomarkers associated with the pathogenesis of idiopathic pulmonary fibrosis

L Wang, M Zhu, Y Li, P Yan, Z Li, X Chen… - Molecular & Cellular …, 2023 - ASBMB
The heterogeneity of idiopathic pulmonary fibrosis (IPF) limits its diagnosis and treatment.
The association between the pathophysiological features and the serum protein signatures …

iTRAQ-based proteomics reveals novel biomarkers for idiopathic pulmonary fibrosis

R Niu, Y Liu, Y Zhang, Y Zhang, H Wang, Y Wang… - PloS one, 2017 - journals.plos.org
Idiopathic pulmonary fibrosis (IPF) is a gradual lung disease with a survival of less than 5
years post-diagnosis for most patients. Poor molecular description of IPF has led to …

Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis–a potential biomarker role for LysoPC

B Rindlisbacher, C Schmid, T Geiser, C Bovet… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology.
Patients present loss of lung function, dyspnea and dry cough. Diagnosis requires …

A system biology study of BALF from patients affected by idiopathic pulmonary fibrosis (IPF) and healthy controls

C Landi, E Bargagli, A Carleo, L Bianchi… - PROTEOMICS …, 2014 - Wiley Online Library
Background Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease
characterized by progressive loss of the alveolar integrity, recruitment, and activation of …

Metabolic dysregulation in idiopathic pulmonary fibrosis

E Bargagli, RM Refini, M d'Alessandro… - International journal of …, 2020 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative disorder limited to the lung. New
findings, starting from our proteomics studies on IPF, suggest that systemic involvement with …

Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs

M Korfei, S Schmitt, C Ruppert, I Henneke… - Journal of proteome …, 2011 - ACS Publications
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease for which no effective
therapy exists to date. To identify the molecular mechanisms underlying IPF, we performed …

[HTML][HTML] Dysregulation of metabolic pathways in pulmonary fibrosis

R Rajesh, R Atallah, T Bärnthaler - Pharmacology & Therapeutics, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …