The effects of diabetes on placental lipase activity in the rat and human

S Kaminsky, CP Sibley, M Maresh, CR Thomas… - Pediatric …, 1991 - nature.com
Lipase activities were measured at pH 4 and pH 8 in the placentas of rats made diabetic by
streptozotocin treatment and also in the placentas of women classified as having 1) impaired …

[HTML][HTML] Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity

AK Anam, KM Cooke, MB Dratver, JV O'Bryan… - Molecular …, 2022 - Elsevier
Objective Maternal obesity increases the incidence of excess adiposity in newborns,
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …

Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta

E Dubé, A Gravel, C Martin, G Desparois… - Biology of …, 2012 - academic.oup.com
Abstract Knowledge of the consequences of maternal obesity in human placental fatty acids
(FA) transport and metabolism is limited. Animal studies suggest that placental uptake of …

Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy

P Díaz, J Harris, FJ Rosario… - American Journal of …, 2015 - journals.physiology.org
Obesity in pregnancy is associated with increased fetal growth and adiposity, which, in part,
is determined by transplacental nutrient supply. Trophoblast uptake and intracellular …

[HTML][HTML] Maternal and fetal lipid metabolism under normal and gestational diabetic conditions

E Herrera, G Desoye - Hormone molecular biology and clinical …, 2016 - degruyter.com
Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …

Increased maternal-fetal transport of fat in diabetes assessed by polyunsaturated fatty acid content in fetal lipids

R Goldstein, E Levy, E Shafrir - Neonatology, 1985 - karger.com
The distribution of fatty acids was determined by gas-liquid chromatography in total lipid and
triglyceride fraction of extracts of several tissues of streptozotocin-diabetic rats and their …

Maternal lipids and fetal overgrowth: making fat from fat

LA Barbour, TL Hernandez - Clinical therapeutics, 2018 - Elsevier
There is increasing recognition that maternal glucose concentrations lower than those
previously used for diagnosis of gestational diabetes mellitus (GDM) and targeted for …

Differences in the implications of maternal lipids on fetal metabolism and growth between gestational diabetes mellitus and control pregnancies

UM Schaefer‐Graf, K Meitzner… - Diabetic …, 2011 - Wiley Online Library
Diabet. Med. 28, 1053–1059 (2011) Abstract Aims To evaluate the potential contribution of
maternal glucose and lipids to fetal metabolic variables and growth in pregnancies with …

Placental fatty acid transport in maternal obesity

I Cetin, F Parisi, C Berti, C Mandò… - Journal of developmental …, 2012 - cambridge.org
Pregestational obesity is a significant risk factor for adverse pregnancy outcomes. Maternal
obesity is associated with a specific proinflammatory, endocrine and metabolic phenotype …

[HTML][HTML] Gestational and hormonal regulation of human placental lipoprotein lipase

AL Magnusson-Olsson, B Hamark, A Ericsson… - Journal of lipid …, 2006 - ASBMB
The fetal demand for FFA increases as gestation proceeds, and LPL represents one
potential mechanism for increasing placental lipid transport. We examined LPL activity and …